LAVENDUSTIN A
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LAVENDUSTIN A Eigenschaften
- Schmelzpunkt:
- 205-215 °C
- Siedepunkt:
- 741.7±60.0 °C(Predicted)
- Dichte
- 1.495±0.06 g/cm3(Predicted)
- RTECS-Nr.
- DG8578950
- storage temp.
- −20°C
- L?slichkeit
- DMSO: soluble
- pka
- 2.31±0.10(Predicted)
- Aggregatzustand
- crystalline
- Farbe
- Yellow to brown
- Sensitive
- Air Sensitive
- Stabilit?t:
- Moisture Sensitive: Hygroscopic
- CAS Datenbank
- 125697-92-9(CAS DataBase Reference)
Sicherheit
Kennzeichnung gef?hrlicher | Xi | ||
---|---|---|---|
R-S?tze: | 36/37/38 | ||
S-S?tze: | 37/39-26 | ||
WGK Germany | 3 | ||
HS Code | 29225000 |
LAVENDUSTIN A Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.S-S?tze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Lavendustin A is a selective inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase (IC50 = 11 nM) that was first isolated from a Streptomyces culture filtrate. It does not inhibit protein kinase A (PKA), PKC, or PI3K (IC50s > 100 μM). It has been used to differentiate rat mesenchymal stem cells, to inhibit NMDA-stimulated cGMP production, and to inhibit VEGF-induced angiogenesis.Chemische Eigenschaften
Off-White SolidBiologische Aktivit?t
Potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC 50 = 11 nM). Inhibits p60 c-src with an IC 50 of 500 nM and is selective over PKA, PKC and PI 3-kinase (IC 50 > 100 μ M).LAVENDUSTIN A Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
LAVENDUSTIN A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 85)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32965 | 60 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 |
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 |
18522618860@163.com | China | 694 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 22787 | 58 |
Alfa Chemistry | |
Info@alfa-chemistry.com | United States | 24072 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6391 | 58 |
TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38631 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
125697-92-9()Verwandte Suche:
- RG14355
- LAVENDUSTIN A
- 5-AMINO-[(N-2,5-DIHYDROXYBENZYL)-N'-2-HYDROXYBENZYL]SALICYLIC ACID
- 5-[[(2,5-DIHYDROXYPHENYL)METHYL][(2-HYDROXYPHENYL)METHYL]AMINO]-2-HYDROXYBENZOIC ACID
- 5-[(2,5-Dihydroxybenzyl)(2-hydroxybenzyl)amino]-2-hydroxybenzoic acid
- Lavendustin A,98%
- NSC 678027
- Benzoic acid,5-[[(2,5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxy-
- Lavendustin A - CAS 125697-92-9 - Calbiochem
- RG-14355;NSC 678027
- LAVENDUSTIN A USP/EP/BP
- Lavendustin A, tyrosine kinase inhibitor
- 125697-92-9
- BioChemical
- Cell Biology
- Cell Signaling and Neuroscience
- Kinase/Phosphatase Biology
- Receptor Tyrosine Kinase Inhibitors
- Tyrosine Kinase (TK)
- Miscellaneous Natural Products
- All Inhibitors
- Inhibitors
- Tyrosine Kinase Inhibitors