LY 223982 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Leukotriene B₄ (LTB₄) is a dihydroxy fatty acid derived from the 5-lipoxygenase pathway of arachidonic acid metabolism and is an important mediator of the inflammatory process. The benzophenone dicarboxylic acid derivative LY223982 is a potent BLT₁ receptor antagonist. It inhibits the specific binding of radiolabeled-LTB₄ to isolated human neutrophils with an IC₅₀ value of 13.2 nM. LY223982 inhibits the leukotriene B₄ (LTB₄)-induced aggregation of guinea pig and human neutrophils with IC₅₀ values of 74 and 100 nM, respectively. However, concentrations of LY223982 up to 10 μM do not inhibit binding of LTB₄ to human BLT₁ or BLT₂ expressed in CHO cells.

Verwenden

LY223982 is a potent P2Y7 (BLT1) receptor antagonist.

LY 223982 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

LY 223982 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19885	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185	sales-cpd@caerulumpharma.com	China	3466	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Angel Pharmatech, Ltd.	17317130613	3358272972@qq.com	China	3253	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9729	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9409	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18478	58

117423-74-2()Verwandte Suche:

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• LY 223982
• 5-(3-Carboxybenzoyl)-2-[(E)-6-(4-methoxyphenyl)-5-hexenyloxy]benzenepropanoic acid
• SYZSSLLFRVDRHL-QPJJXVBHSA-N
• LY223982 Exclusive
• LY223982 (Synonyms: CGS23131
• SKF107324)
• CGS23131
• Benzenepropanoic acid, 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]-
• LY223982,LY-223982
• 117423-74-2