4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt
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- CAS-Nr.
- 206443-06-3
- Englisch Name:
- 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt
- Synonyma:
- 4-Methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-;4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt;4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt;4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate sodium salt;4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt;4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt;[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfate;4-Methyl-7-[(6-O-sulfo-beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one monosodium salt;2H-1-Benzopyran-2-one, 4-methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-, monosodium salt (9CI);[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methoxysulfonyloxysodium
- CBNumber:
- CB21231629
- Summenformel:
- C16H17NaO11S
- Molgewicht:
- 440.35435
- MOL-Datei:
- 206443-06-3.mol
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4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Eigenschaften
- Schmelzpunkt:
- 196-198?C
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- L?slichkeit
- Methanol (Slightly, Sonicated), Water (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Stabilit?t:
- -20?C Freezer, Under Inert Atmosphere
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify
N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
Chemische Eigenschaften
White Solid
Verwenden
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt is used for the determination of galactose-6-sulphate sulphatase activity,it is used in the diagnosis of Mucopolysaccharidosis IV A.
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 40)Lieferanten
- 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt
- 4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt
- 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt
- 4-Methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-
- 4-Methyl-7-[(6-O-sulfo-beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one monosodium salt
- [(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfate
- [(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methoxysulfonyloxysodium
- 4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt
- 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate sodium salt
- 2H-1-Benzopyran-2-one, 4-methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-, monosodium salt (9CI)
- 206443-06-3
- C16H17NaO11S
- C16H18O11SNa
- Carbohydrates & Derivatives
- Fluorescent Labels & Indicators
