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ACIFRAN

ACIFRAN Struktur
72420-38-3
CAS-Nr.
72420-38-3
Englisch Name:
ACIFRAN
Synonyma:
ACIFRAN;ay25712;Acifranum;4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci;4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid;4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID;5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid;2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-;(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
CBNumber:
CB2121167
Summenformel:
C12H10O4
Molgewicht:
218.21
MOL-Datei:
72420-38-3.mol

ACIFRAN Eigenschaften

Schmelzpunkt:
176°
Siedepunkt:
378.4±42.0 °C(Predicted)
Dichte
1.343±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
L?slichkeit
Soluble in DMSO > 10 mM
Aggregatzustand
Powder
pka
2.25±0.40(Predicted)
Farbe
Off-white to light yellow

Sicherheit

Toxizit?t LD50 orally in rats: 3 g/kg (Jirkovsky, 1982)

ACIFRAN Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Antihyperlipopro-teinemic.

Trademarks

Reductol (Wyeth-Ayerst).

Biologische Aktivit?t

Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.

ACIFRAN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2H-Pyran-2,3,5(4H,6H)-trione, 6-methyl-6-phenyl-

Downstream Produkte

ACIFRAN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 43)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32159 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
 sales@rechemscience.com China 2994 58
BOC Sciences --
 info@bocsci.com USA 0 65
Changzhou Chenhong Biotechnology Co., Ltd. 0519-85788828 13775037613
 sales@chemrenpharm.com China 3600 58
Shanghai Universal Biotech Co.,Ltd 13774214275
 zhouzz@univ-bio.com China 24998 58
Beijing Biocreative Technology Co., Ltd. 15522676233
 3007606172@qq.com China 1248 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24641 58

72420-38-3()Verwandte Suche:

  • ay25712
  • ACIFRAN
  • 4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID
  • (R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
  • 4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
  • Acifranum
  • 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci
  • 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid
  • 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-
  • 72420-38-3
  • Miscellaneous Compounds
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