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Thalidomide-NH-CH2-COOH

Thalidomide-NH-CH2-COOH Struktur
927670-97-1
CAS-Nr.
927670-97-1
Englisch Name:
Thalidomide-NH-CH2-COOH
Synonyma:
Thalidomide-NH-CH2-COOH;Thalidomide-4-NH-C1-COOH;6-dioxopiperidin-3-yl)-1;3-dioxoisoindolin-4-yl)glycine;Thalidomide-NH-CH2-COOH, 10 mM in DMSO;3-dioxoisoindol-4-yl]amino]acetic acid;(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine;2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]acetic acid;Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;[(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)amino]acetic acid
CBNumber:
CB18197022
Summenformel:
C15H13N3O6
Molgewicht:
331.28
MOL-Datei:
927670-97-1.mol

Thalidomide-NH-CH2-COOH Eigenschaften

Siedepunkt:
713.9±60.0 °C(Predicted)
Dichte
1.637±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO : 50 mg/mL (150.93 mM; Need ultrasonic)
pka
3.92±0.10(Predicted)
Aggregatzustand
Solid
InChI
InChI=1S/C15H13N3O6/c19-10-5-4-9(13(22)17-10)18-14(23)7-2-1-3-8(12(7)15(18)24)16-6-11(20)21/h1-3,9,16H,4-6H2,(H,20,21)(H,17,19,22)
InChIKey
LRGLFYOYKPSPJQ-UHFFFAOYSA-N
SMILES
C(O)(=O)CNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

Sicherheit

Thalidomide-NH-CH2-COOH Chemische Eigenschaften,Einsatz,Produktion Methoden

Definition

Thalidomide-NH-CH2-COOH contains a thalidomide group, an amide, an alkylC2 chain, and a terminal carboxylic acid. This product is ready for conjugation to target proteins for PROTAC R&D. It is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. This compound also can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937).

Thalidomide-NH-CH2-COOH Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Thalidomide-NH-CH2-COOH Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 33)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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CR Corporation Limited 		+8613062833949
 fred.wen@crcorporation.cn China 8647 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Zhengzhou Lingzhiyue Technology Co., Ltd 		+86-0371-55074660 +86-13783527580
 Lingzhiyue@aliyun.com China 3145 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43340 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658
 sales1@artkmedchem.com China 39004 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865
 han_yajun@dctc.daicel.com China 6791 65
Jilin Province Woda Biotechnology Co., Ltd. 13504435624
 1927928688@qq.com China 1466 58
Lingyuan Bebiansen Biological Technology Co., Ltd 18642120371
 2837458851@qq.com China 7995 58
Shandong Territorial sea Biological Technology Co., LTD 15092083467
 18660263263@163.com China 2472 58
  • Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
  • [(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)amino]acetic acid
  • Thalidomide-NH-CH2-COOH
  • 3-dioxoisoindol-4-yl]amino]acetic acid
  • 3-dioxoisoindolin-4-yl)glycine
  • 6-dioxopiperidin-3-yl)-1
  • (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine
  • inhibit,Ligands for E3 Ligase,E3 ligase-recruiting Moiety,Inhibitor,Thalidomide NH CH2 COOH,ThalidomideNHCH2COOH,cereblon,Thalidomide-NH-CH-2-COOH,CRBN,Thalidomide
  • 2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]acetic acid
  • Thalidomide-4-NH-C1-COOH
  • Thalidomide-NH-CH2-COOH, 10 mM in DMSO
  • 927670-97-1
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