Fumonisin B1 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R40:Verdacht auf krebserzeugende Wirkung.
R36:Reizt die Augen.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R11:Leichtentzündlich.

S-S?tze Betriebsanweisung:

S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S16:Von Zündquellen fernhalten - Nicht rauchen.

Chemische Eigenschaften

white to tan powder

Verwenden

Fumonisin B1 is a major analogue of a family of potent mycotoxins produced by various Fusarium species, associated with animal toxicity worldwide. In vitro, fumonisin B1 inhibits sphingosine N-acyl-transferase (ceramide synthase) and blocks the growth of axons.

Allgemeine Beschreibung

Fumonisin B₁ is a neurotoxin and a phytotoxin. A cell-permeable mycotoxin that inhibits sphingolipid biosynthesis in rat kidney and in liver microsomes by inhibition of sphingosine N-acyltransferase (ceramide synthase) (IC₅₀ = 100 nM). Cellular effects also appear to be induced by micromolar levels of FB₁. Because it inhibits ceramide synthase activity, it elevates cellular levels of sphingoid bases, including sphinganine, resulting in overall inhibition of sphingolipid biosynthesis. Preferentially inhibits sphingomyelin biosynthesis in neuronal cells. Has carcinogenic properties.

Biologische Aktivit?t

Mycotoxin produced by Fusarium moniliforme . Potently inhibits sphingosine N-acyltransferase (ceramide synthase), causing an accumulation of sphingoid bases (IC 50 ~ 75 nM). Also inhibits protein phosphatases; IC 50 values are 80, 300, 400, 500 and 3000 μ M for PP5, PP2C α , PP2A, PP1 γ 2 and PP2B respectively.

Fumonisin B1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Fumonisin B1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32820	60
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32002	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10319	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	86 18062405514 18062405514	ada@ipurechemical.com	CHINA	3461	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19741	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 13675144456	sean.lv@synzest.com	China	11438	58
Zhejiang Huida Biotech Co., LTD	0571-89903882 13626641628	jiangnan@huidabiotech.com	China	3656	58

116355-83-0(Fumonisin B1)Verwandte Suche:

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• MACROFUSINE
• FUMONISIN B1
• FUMONISIN B1, FUSARIUM MONILIFORME
• FB1
• 1,2,3-PROPANETRICARBOXYLIC ACID 1,1'-[1-(12-AMINO-4,9,11-TRIHYDROXY-2-METHYLTRIDECYL)-2-(1-METHYLPENTYL)-1,2-ETHANEDIYL] ESTER
• 1,2,3-PROPANETRICARBOXYLIC ACID 1,1'-[12-AMINO-4,9,11-TRIHYDROXY-2-METHYLTRIDECYL)-2-(1-METHYLPENTYL)-1,2-ETHANEDIYL]ESTER
• 1,2,3-propanetricarboxylicacid,1,1’-(1-(12-amino-4,9,11-trihydroxy-2-methyltr
• idecyl)-2-(1-methylpentyl)-1,2-ethanediyl)ester
• FUMONISIN B1 (MACROFUSINE) \ SPHINGOSINE
• FUMONISIN B1 FROM FUSARIUM MONILIFORME
• 1,2,3-Propanetricarboxylic acid, 1,1[1-(12-amino-4,9,11-trihydroxy-2-methyl-tridecyl)-2-(1-methylpentyl)-1,2-ethane-diyl]ester, Macrofusine
• FumonisinB1 from Fusarium moniliforme, Macrofusine
• Fumonisin B1,96%
• 1,1'-[(1S,2R)-1-[(2S,4R,9R,11S,12S)-12-Amino-4,9,11-trihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl-1,2,3-(2R,2'R)-propanetricarboxylicacidester.
• Fumonisin B1 ,95%
• FuMonisin B1, 96% 1MG
• (2R,2'R)-1,2,3-Propanetricarboxylic Acid 1,1'-[(1S,2R)-1-[(2S,4R,9R,11S,12S)-12-AMino-4,9,11-trihydroxy-2-Methyltridecyl]-2-[(1R)-1-Methylpentyl]-1,2-ethanediyl] Ester
• FUMONISIN B1 98%
• 1,2,3-Propanetricarboxylic acid, 1,1-(1S,2R)-1-(2S,4R,9R,11S,12S)-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-(1R)-1-methylpentyl-1,2-ethanediyl ester, (2R,2R)-
• fumonisin b1solution
• Fumonisin B1 (2R,2'R)-1,2,3-Propanetricarboxylic acid 1,1'-[(1S,2R)-1-[(2S,4R,9R,11S,12S)-12-amino-4,9,11-trihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] ester
• Standard Solution Fumonisin B1
• Fumonisin B1 (FB1)
• Fumonisin B, Fusarium moniliforme - CAS 116355-83-0 - Calbiochem
• Fumonisin B1 Ready Made Solution
• Fumonisin B1, 96%, from Fusarium moniliforme
• Fumonisin B1 Solution [ 50μg/ml Acetonitrile:Water(1:1) Solution]
• Fumonisin B1 50ug /ml in ACN:H2O 1:1
• B1 Fumonisin B1
• (2R)-2-(2-{[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-{[(3R)-3,4-dicarboxybutanoyl]oxy}-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy}-2-oxoethyl)butanedioic acid
• Fumonisine B1 in Acetonitrile
• Fumonisin B1 50 μg/ml Acetonitrile/Water
• Fumonisine B1 in Acetonitrile:Water=1:1
• 116355-83-0
• C34H59NO15
• Biochemicals and Reagents
• BioChemical
• Enzyme Inhibitors by Enzyme
• Enzymes, Inhibitors, and Substrates
• Enzyme Inhibitors
• R to Z
• Sphingosine N-acyltransferase
• antibiotic
• Miscellaneous Natural Products
• Amines
• Chiral Reagents
• Intermediates & Fine Chemicals
• Pharmaceuticals