L-701,324
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- CAS-Nr.
- 142326-59-8
- Englisch Name:
- L-701,324
- Synonyma:
- L-701;CS-2045;L-701,324;L-701,304;L 701324, glycine site NMDA receptor antagonist;7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(H)-quinolinone;7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one;7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE;7-chloro-1-(4-hydroxy-3-phenoxyphenyl)quinolin-2(1H)-one;7-CHLORO-4-HYDROXY-3-(3-PHENOXY )PHENYLQUINOLIN-2[1H]-ONE
- CBNumber:
- CB1757589
- Summenformel:
- C21H14ClNO3
- Molgewicht:
- 363.79
- MOL-Datei:
- 142326-59-8.mol
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L-701,324 Eigenschaften
- Schmelzpunkt:
- 308 °C
- Siedepunkt:
- 584.7±50.0 °C(Predicted)
- Dichte
- 1.389±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMSO: soluble36.4mg/mL
- Aggregatzustand
- solid
- pka
- 4.50±1.00(Predicted)
- Farbe
- White to off-white
L-701,324 Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
L-701,324 is a potential anticonvulsant with high selectivity and affinity for the NMDA receptor glycine site. NMDA receptors are expressed by small-cell lung cancer and are potential targets for effective treatment.
Biologische Aktivit?t
An orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor.
L-701,324 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
L-701,324 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 81)Lieferanten
142326-59-8()Verwandte Suche:
- 7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE
- 7-CHLORO-4-HYDROXY-3-(3-PHENOXY )PHENYLQUINOLIN-2[1H]-ONE
- 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(H)-quinolinone
- L-701,304
- 7-chloro-1-(4-hydroxy-3-phenoxyphenyl)quinolin-2(1H)-one
- L-701
- L-701,324
- CS-2045
- 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one
- 2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-
- L-701324,Ionotropic glutamate receptors,inhibit,Inhibitor,tail suspension test,chronic unpredictable mild stress,antidepressant,forced swim test,iGluR,glycine B binding site,brain membranes,L 701324
- 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1,2-dihydroquinolin-2-one
- L 701324, glycine site NMDA receptor antagonist
- 142326-59-8
- C21H14CINO3
- Ionotropic Glutamate Receptor Modulators
- Ion Channels
- Ligand-Gated Ion Channels
- Cell Signaling and Neuroscience
- Cell Biology
- BioChemical
- Inhibitors
