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(5α,25R)-Spirostan-3β-ol

Tigogenin Struktur
77-60-1
CAS-Nr.
77-60-1
Bezeichnung:
(5α,25R)-Spirostan-3β-ol
Englisch Name:
Tigogenin
Synonyma:
Nsc93754;TIGOGENIN;Ticogenin;Sisalagenin;TIGOGENIN90%;Tigogenin-RM;Sisal saponin;Spirostan-3-ol;SMILAGENIN(RG);Trigonegenin B
CBNumber:
CB1669512
Summenformel:
C27H44O3
Molgewicht:
416.64
MOL-Datei:
77-60-1.mol

(5α,25R)-Spirostan-3β-ol Eigenschaften

Schmelzpunkt:
202-204°C
alpha 
-68 º (c=0.8g/100ml, CHCl3)
Siedepunkt:
474.91°C (rough estimate)
Dichte
1.0362 (rough estimate)
Brechungsindex
1.4700 (estimate)
storage temp. 
-20°C Freezer, Under inert atmosphere
L?slichkeit
Chloroform (Slightly)
Aggregatzustand
Solid
pka
15.14±0.70(Predicted)
Farbe
Off-White
Optische Aktivit?t
-67.218 (c 1, CHCl3)
CAS Datenbank
77-60-1(CAS DataBase Reference)
NIST chemische Informationen
Tigogenin(77-60-1)

Sicherheit

RTECS-Nr. WH1443500

(5α,25R)-Spirostan-3β-ol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Tigogenin is a steroidal sapogenin that has been found in A. sisalana and has diverse biological activities. It increases the proliferation rate of, as well as mRNA levels of genes encoding the osteoblastic differentiation markers Cbfa1, collagen type I, and osteocalcin in, mouse bone marrow stromal cells (BMSCs) in a concentration-dependent manner. It also increases matrix calcium deposition in BMSCs when used at concentrations of 30 and 90 μM. Tigogenin is active against the fungus A. fumigatus (MIC50 = 16 μg/ml). It inhibits carrageenan-induced paw edema in rats when administered at a dose of 4.2 μg/kg.

Chemische Eigenschaften

mp 196-208C° LOD ≤0.5%

Verwenden

Tigogenin is a saponin structurally similar to Diosgenin (D484700) and acts as a natural plant steroid which induces apoptosis in rheumatoid arthritic fibroblast-like synoviocytes.

(5α,25R)-Spirostan-3β-ol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(5α,25R)-Spirostan-3β-ol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 225)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29884 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
Shanghai Standard Technology Co., Ltd.
18502101150
ft-sales@nature-standard.com CHINA 1923 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58

77-60-1((5α,25R)-Spirostan-3β-ol)Verwandte Suche:


  • TIGOGENIN
  • (25r)-5-alpha-spirostan-3-beta-o
  • 25R,5ALPHA-SPIROSTAN-3BETA-OL
  • 5-ALPHA, 20-ALPHA, 22-ALPHA, 25D-SPIROSTAN-3-BETA-OL
  • (25R)-5-Spirostan-3-ol
  • (3-beta,5-alpha,25r)-spirostan-3-o
  • 5-alpha-spirostan-3-beta-ol
  • 5alpha-Spirostan-3beta-ol, (25R)-
  • Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran], spirostan-3-ol deriv.
  • Spirostan-3-ol
  • Spirostan-3-ol, (3beta,5alpha,25R)-
  • Ticogenin
  • Tsosarsasaprgein
  • (5alpha,25R)-spirostan-3beta-ol
  • TIGOGENIN90%
  • SMILAGENIN(RG)
  • (3,5,25R)-3-Hydroxy-spirostane
  • (3-beta,5-alpha,25r)-spirostan-3-ol
  • TIGOGENIN (91%: 95%) (5A,25R)-SPIROSTAN-3B-OL)
  • Sisalagenin
  • (25R)-5a-Spirostan-3b-ol
  • (25R)-3β-Hydroxy-5α-spirostane
  • Trigonegenin B
  • Nsc93754
  • 22-Isoallospirostan-3β-ol
  • (2aS,2'R,4S,5'R,6aS,6bS,8aS,8bR,9S,11aS,12aS,12bR)-5',6a,8a,9-TetraMethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-ol
  • 22-Isoallospirostan-3β-ol
  • (25R)-5.α.-Spirostan-3.β.-ol
  • (2aS,4S,5'R,6aS,6bS,8aS,8bR,9S,10R,11aS,12aS,12bR)-5',6a,8a,9-Tetramethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-ol
  • 5α, 20α, 22α, 25D-SPIROSTAN-3β-OL
  • Sisal saponin
  • (2aS,4S,5'R,6aS,6bS,8aS,8bR,9S,10R,11aS,12aS,12bR)-5',6a,8a,9-Tetramethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-ol
  • Tigogenin-RM
  • 77-60-1
  • Miscellaneous Natural Products
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