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Ciclacillin

CYCLACILLIN (200  MG) Struktur
3485-14-1
CAS-Nr.
3485-14-1
Bezeichnung:
Ciclacillin
Englisch Name:
CYCLACILLIN (200 MG)
Synonyma:
wy4508;Calthor;Vipicil;Wyvital;Vatracin;cyclapen;NSC 88789;Citosarin;CICLACILIN;vastcillin
CBNumber:
CB1501397
Summenformel:
C15H23N3O4S
Molgewicht:
341.43
MOL-Datei:
3485-14-1.mol

Ciclacillin Eigenschaften

Schmelzpunkt:
182-183° (anhydrate) (Hou, Poole); mp 156-158° (dec) (Alburn et al.)
alpha 
D25 +268° (water)
Siedepunkt:
649.6±55.0 °C(Predicted)
Dichte
1.40±0.1 g/cm3(Predicted)
L?slichkeit
Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
pK1, pK2 in water: 2.68, 7.50; in 50% dioxane: 4.16, 7.04(at 25℃)
Farbe
White to Off-White
Wasserl?slichkeit
32g/L(25 ºC)
Stabilit?t:
Hygroscopic

Sicherheit

Ciclacillin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ciclacillin was synthesized by Wyeth Laboratories in 1967 in the course of studies on the improvement of oral absorption of ampicillin. Although its antibacterial activity is one-sixteenth to one-half that of ampicillin, it shows a four to tenfold higher oral absorption and higher urinary excretion. Ciclacillin shows less tendency than ampicillin to cause diarrhea and is used for therapy of pyoderma, wound infection, respiratory and urinary tract infections, as well as ear and nose, and other infections caused by Staphylococcus, Streptococcus, Escherichia coli, Citrobacter, Klebsiella, Proteus, and Haemophilus influenzae.

Verwenden

Antibacterial.

Antimicrobial activity

The structure differs from other aminopenicillins in that the benzene ring is completely saturated and the amino substituent is attached directly to it instead of being linked to an adjacent carbon atom. It is less active than ampicillin against staphylococci, streptococci and H. influenzae, but is better absorbed by mouth, peak plasma levels of 10–18 mg/L being reached after a 500 mg oral dose. Its pharmacokinetic properties, side effects and use resemble those of ampicillin. It has limited availability.

Ciclacillin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Ciclacillin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 16)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387
1057@dideu.com China 3958 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167
1026@dideu.com China 7724 58
BOC Sciences 1-631-485-4226; 16314854226
info@bocsci.com United States 14055 65
Beijing HuaMeiHuLiBiological Chemical 010-56205725
waley188@sohu.com China 12335 58
BOC Sciences 16314854226
info@bocsci.com United States 9923 65
Zhejiang Huida Biotech Co., LTD 0571-89903882 13626641628
jiangnan@huidabiotech.com China 3656 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44918 58
Zhejiang Huida Biotech Co., LTD 0571-0571-89903882 15990081639
sunshixuan@huidabiotech.com China 3705 58

3485-14-1(Ciclacillin)Verwandte Suche:


  • (2S-(2-a,5a,6b))-6-((1-Aminocyclohexyl)carbonyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(1-aminocyclohexanecarboxamido)-3,3-dimethyl-7-oxo- (7CI, 8CI)
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(1-aminocyclohexyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(1-aminocyclohexyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, [2S-(2a,5a,6b)]-
  • 6-(1-Aminocyclohexylcarboxamido)penicillanic acid
  • Calthor
  • Citosarin
  • NSC 88789
  • Penicillin, (aminocyclohexyl)-
  • Syngacillin
  • Vatracin
  • Vipicil
  • Wyvital
  • CICLACILIN
  • (5β)-6α-(1-Aminocyclohexylcarbonylamimo)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid
  • ciclacillin
  • ciclacillum
  • cyclacillin
  • cyclapen
  • ultracillin
  • vastcillin
  • wy4508
  • (1-aminocyclohexyl)penicillin
  • 6-(1-aminocyclohexanecarboxamido)penicillanicacid
  • aminocyclohexylpenicillin
  • CYCLACILLIN (200 MG)
  • CYCLACILLIN (200 MG) USP/EP/BP
  • CYCLACILLIN USP/EP/BP
  • 3485-14-1
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