DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ortho Evra@ is the first birth control transdermal patch and contains a combination of norelgestromin and ethinylestradiol. The patch can be applied to the buttocks, lower abdomen, upper torso or arms; changed weekly for 3 weeks, followed by a patch-free week. Norelgestromin is the active metabolite produced following oral administration of norgestimate, the progestin component of the contraceptive, Ortho-Cyclen^?. The half-life value of norelgestromin was approximately 28 h. Following application, norelgestromin rapidly appeared in the serum, reached a plateau by approximately 48h and was maintained at an approximate steady state throughout the wear period. Hepatic metabolites of norelgestromin included norgestrel and various hydroxylated and conjugated metabolites that were eliminated by renal and fecal pathways. Ortho Evra produced ovarian suppression and cycle control. It was significantly more effective in suppressing follicular development than the leading oral contraceptive Triphasil^? (ethinyl estradiol/levomorgestrel); was as effective in preventing pregnancies and had similar tolerability profile. The patch offers 99% efficacy when used appropriately, as shown by three clinical trials. However, a statistically significantly greater proportion of pregnancies occurred among women weighing 90 kg or more. Ortho Evra^? was well tolerated, with 2.6% of women discontinuing treatment due to mild to moderate reactions at the site of application. Thus, the patch combined the efficacy of oral contraceptives with the convenience of just once-weekly dosing.

Chemische Eigenschaften

White Solid

DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33338	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
Guangzhou Tosun Pharmaceutical Ltd	+86-020-61855200-902 +8618124244216	info@upharm.cn	China	835	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	94657	76
LGM Pharma	1-(800)-881-8210	inquiries@lgmpharma.com	United States	2123	70
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50

53016-31-2()Verwandte Suche:

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• (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one OxiMe
• (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one-d6 OxiMe
• (-)-NorelgestroMin-d6
• (17alpha)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one oxime
• (E)- and (Z)-17-Deacetylnorgestimate mixture
• Norgestimate metabolite Norelgestromin
• 17-Desacetyl Norgestimate ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)
• Deacetylnorgestimate (Mixture of (E)- And (Z)-17-Deacetyl Norgestimate)
• (17R)-13-Ethyl-17-hydroxy-18,19-dinor-pregna-4-ene-20-yne-3-oneoxime
• [17R,(+)]-17-Hydroxy-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one oxime
• [17R,(+)]-17-Hydroxy-13-ethyl-18,19-dinorpregna-4-ene-20-yne-3-oneoxime
• Desacetylnorgestimate
• DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)
• ,10-alpha,13-alpha,14-beta)-
• 18,19-dinorpregn-4-en-20-yn-3-one,13-ethyl-17-hydroxy-,oxime,(8-alpha,9-beta
• levonorgestreloxime
• 17-Deacetylnorgestimate
• (17a)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one Oxime
• 18-Methylnorethindrone oxime
• BRN 4202099
• D-Norgestrel 3-oxime
• Levonorgestrel 3-oxime
• RWJ 10553
• 13-ETHYL-17_-HYDROXY-18,19-DINORPREGN-4-EN-20-YN-3-ONE OXIME
• 17-Desacetyl Norgestimate Solution, 100ppm
• 17-Desacetyl Norgestimate (Mixture of Isomers)
• 17-Deacylnorgestimate
• 17-Desacetyl Norgestimate-d7 (Mixture ofIsomers) (Norelgestromin-d7)
• 17-Desacetyl Norgestimate (Mixture of Isomers) (Norelgestromin)
• 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, oxime, (17α)-
• (E/Z)-17-Deacetylnorgestimate
• 17-Desacetyl NorgestimateQ: What is 17-Desacetyl Norgestimate Q: What is the CAS Number of 17-Desacetyl Norgestimate Q: What is the storage condition of 17-Desacetyl Norgestimate Q: What are the applications of 17-Desacetyl Norgestimate
• Norelgestromin (1468454)
• Deacetylnorgestimate ((E)- and (Z)-17-deacetyl norgestimate mixture) (1471958)
• Deacetylnorgestimate (Mixture of (E)- And (Z))
• Drug Metabolite,inhibit,Inhibitor,Norgestimate metabolite Norelgestromin
• Deacetylnorgestimate ((E)- and (Z)-17-deacetyl norgestimate mixture)
• (8R,9S,10R,13S,14S,17R,E)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one oxime
• Deacetylnorgestimate (25 mg) ((E)- and (Z)-17-deacetyl norgestimate mixture) (PLANNED TO BE DISCONTINUED)
• Norgestimate metabolite Norelgestromin (mixture of isomers)
• 53016-31-2
• Various Metabolites and Impurities
• Intermediates & Fine Chemicals
• Metabolites & Impurities
• Pharmaceuticals
• Steroids