4-Formylphenylboronic acid
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- CAS-Nr.
- 87199-17-5
- Englisch Name:
- 4-Formylphenylboronic acid
- Synonyma:
- FPBA;4-FORMYLBENZENEBORONIC ACID;AKOS BRN-0111;TIMTEC-BB SBB004077;RARECHEM AH PB 0193;4-Formylphenylboroni;4-Formylboronic acid;4-BORONOBENZALDEHYDE;Metoprolol Impurity 34;Formylphenylboronic acid
- CBNumber:
- CB1491072
- Summenformel:
- C7H7BO3
- Molgewicht:
- 149.94
- MOL-Datei:
- 87199-17-5.mol
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4-Formylphenylboronic acid Eigenschaften
- Schmelzpunkt:
- 237-242 °C (lit.)
- Siedepunkt:
- 347.6±44.0 °C(Predicted)
- Dichte
- 1.24±0.1 g/cm3(Predicted)
- Dampfdruck
- 0Pa at 25℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- <10g/l
- Aggregatzustand
- Liquid
- pka
- 7.34±0.10(Predicted)
- Farbe
- Clear colorless to yellow-orange
- PH
- 5.5 (1g/l, H2O, 20℃)
- Wasserl?slichkeit
- Slightly Soluble in water.
- Sensitive
- Air Sensitive
- BRN
- 3030770
- InChIKey
- VXWBQOJISHAKKM-UHFFFAOYSA-N
- LogP
- 1.36 at 20℃
- CAS Datenbank
- 87199-17-5(CAS DataBase Reference)
- EPA chemische Informationen
- Boronic acid, (4-formylphenyl)- (87199-17-5)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P272 |
Kontaminierte Arbeitskleidung nicht au?erhalb des Arbeitsplatzes tragen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P333+P313 |
Bei Hautreizung oder -ausschlag: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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4-Formylphenylboronic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R34:Verursacht Ver?tzungen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white to light yellow crystal powder
Verwenden
4-Formylphenylboronic acid is a substrate for Suzuki cross-coupling reactions and it can be used as a reagent for:
- Palladium-catalyzed Suzuki-Miyaura cross-coupling in water.
- Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides.
- Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids.
- Triethylamine-catalyzed three-component Hantzsch condensations.
- Copper-catalyzed nitrations.
- Oxidative mono-cleavage of dialkenes catalyzed by Trametes hirsuta.
- Palladacycle-catalyzed cross-coupling of arylboronic acids with carboxylic anhydrides or acyl chlorides.
- Palladium-catalyzed aerobic oxidative cross-coupling reactions.
- The synthesis of sensitizers with dithiafulvenyl unit as electron donor for high-efficiency dye-sensitized solar cells.
- The synthesis of a novel protein synthesis inhibitor active against Gram-positive bacteria.
- The Suzuki aryl-aryl coupling of the upper rim of hexahomotrioxacalix[3]arene.
- A rhodium-catalyzed cyclization, converting 1,5-enynes to cyclopentenes and spiro-cyclopentenes.
Synthese
Potassium phenyltrifluoroborate (184 mg, 1.00 mmol) was added to a solution of iron trichloride (185 mg, 1.10 mmol) in 3 mL of 1:1 THF/water. The mixture was stirred at room temperature for 30 min. The reaction mixture was then passed through a short column containing neutral absorption alumina. The alumina was then washed with a mixture of ethyl acetate/hexanes (2:1) to obtain 4-Formylphenylboronic acid (105 mg, 86%). [The boronic acid products can also be isolated by simple extraction techniques.]
4-Formylphenylboronic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-THIOPHEN-2-YL-BENZALDEHYDE
1,3,5-Tris(p-formylphenyl)benzene
(2-(4-vinylphenyl)ethene-1,1,2-triyl)tribenzene
3,4'-DIHYDROXYFLAVONE
4-(2-Cyanophenyl)benzaldehyde
4-AMINOMETHYLPHENYLBORONIC ACID, PINACOL ESTER, HCL
4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID
4-(2-PHENYLETH-1-YNYL)BENZALDEHYDE
Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir
URMC-099
(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol
4-Formylphenylboronic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 534)Lieferanten
87199-17-5()Verwandte Suche:
- RARECHEM AH PB 0193
- TIMTEC-BB SBB004077
- P-FORMYLPHENYLBORONIC ACID
- AKOS BRN-0111
- 4-FORMYLPHENYLBORONIC ACID
- 4-BORONOBENZALDEHYDE
- 4-(Dihydroxyboryl)benzaldehyde, 4-Boronobenzaldehyde
- 4-Formylboronic acid
- 4-Formylphenylboronic acid ,97%
- 4-Formylphenylboronic acid,4-(Dihydroxyboryl)benzaldehyde, 4-Boronobenzaldehyde
- 4-Formylphenylboroni
- 4-ForMylphenylboronic acid, 97% 1GR
- Benzeneboronic acid, p-forMyl- (6CI,7CI)
- 4-ForMylphenylboronic acid >=95.0%
- 4-Formylphenylboronic acid
4-(Dihydroxyboryl)benzaldehyde
- p-Formylbenzeneboronic acid
- (4-methanoylphenyl)boronic acid
- Boronic acid, (4-formylphenyl)-
- 4-(dihydroxyboryl)benzaldehyde
- BENZALDEHYDE-4-BORONIC ACID
- 4-Boronobenzaldehyde~4-Formylphenylboronic acid
- 4-Formylpenylboronic Acid
- Boronic acid, (4-formylphenyl)- (9CI)
- 4-Formylbenzeneboronicacid,97%
- 4-Formylphenylboronic acid(FPBA)
- 2,4-DINITROTOLUENE,1X1ML, ACN 1000UG/ML
- PARAFORMYLPHENYLBORONIC ACID
- 4-FORMYLPHENYLBORONIC ACID, 98+%
- 4-Formylphenlboronic acid
- 4-Formylphenylboronic Acid (contains varying amounts of Anhydride)
- Boronic acid, B-(4-formylphenyl)-
- 4-Formylphenylboronic Acid extrapure, 95%
- 4-FORMYLBENZENEBORONIC ACID
- FPBA
- 4-Formylphenylboronic acid (4-FPBA)
- Metoprolol Impurity 34
- Formylphenylboronic acid
- 87199-17-5
- 87199-17-2
- Boronic Acids
- B (Classes of Boron Compounds)
- BORONIC ACID
- Boronic Acids and Derivatives
- Aryl
- Organometallic Reagents
- Substituted Boronic Acids
- Boron, Nitrile, Thio,& TM-Cpds
- Carbonyl Compounds
- ALDEHYDE
- Aldehydes
- blocks
- BoronicAcids
- Boronic Acid series
- Aryl
- Organoborons
- B (Classes of Boron Compounds)
- CHIRAL CHEMICALS
- Boronic Acids & Esters
