4-Brom-3-methylbenzoesure
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- CAS-Nr.
- 7697-28-1
- Bezeichnung:
- 4-Brom-3-methylbenzoesure
- Englisch Name:
- 4-Bromo-3-methylbenzoic acid
- Synonyma:
- Fluralaner-017;4-Bromo-3-methyl;RARECHEM AL BO 1293;4-Bromo-3-methylbenz;4-BROMO-M-TOLUIC ACID;Fluralaner Impurity 37;4-Bromo-3-methylbenzoicaci;4-BROMO-3-METHYLBENZOIC ACID;3-methyl-4-bromobenzoic acid;Benzoic acid, 4-bromo-3-methyl-
- CBNumber:
- CB1489499
- Summenformel:
- C8H7BrO2
- Molgewicht:
- 215.04
- MOL-Datei:
- 7697-28-1.mol
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4-Brom-3-methylbenzoesure Eigenschaften
- Schmelzpunkt:
- 212-216 °C(lit.)
- Siedepunkt:
- 311.4±30.0 °C(Predicted)
- Dichte
- 1.599±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.04±0.10(Predicted)
- Aggregatzustand
- Powder
- Farbe
- Yellow to orange to tan
- BRN
- 2356649
- InChIKey
- KWVXDZLVCISXIB-UHFFFAOYSA-N
- CAS Datenbank
- 7697-28-1(CAS DataBase Reference)
4-Brom-3-methylbenzoesure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Synthese
A suspension of 4-Amino-3-methylbenzoic acid (73 g, 0.483 mol) in water (411 mL) and 47percent HBr (486 mL) was stirred at 25 ℃ for 1 h and then the reaction mixture was cooled to -2 ℃. A solution of sodium nitrate (32 g, 0.463 mol) in water (100 mL) was added to the reaction mixture over 15 min, maintaining the temperature at -1 ℃ to -2°C. The reaction mixture was stirred at -1 ℃ to -2 ℃ for 1.5h. The reaction mixture was added slowly to a suspension of copper(l)bromide (73 g, 0.508 mol) in water (73 mL) and aqueous HBr (73 mL). The reaction mixture was stirred at 250C for 1 h and then digested at 70 °C for 1 h. The solid was filtered, washed with water till the pH of the filtrate was 7 and dried to obtain 4-Bromo-3-methylbenzoic acid.
4-Brom-3-methylbenzoesure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Brom-3-methylbenzoesure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 287)Lieferanten
7697-28-1(4-Brom-3-methylbenzoesure)Verwandte Suche:
- 3-methyl-4-bromobenzoic acid
- 4-Bromo-3-methyl
- 4-BROMO-M-TOLUIC ACID
- 4-BROMO-3-METHYLBENZOIC ACID
- RARECHEM AL BO 1293
- 4-Bromo-3-methylbenz
- 2-Bromo-5-carboxytoluene, 4-Bromo-m-toluic acid
- 3 - Methyl - 4 - broMine benzoic acid
- Benzoic acid, 4-bromo-3-methyl-
- 4-Bromo-3-methylbenzoic Acid >
- 4-Bromo-3-methylbenzoicaci
- CAS 7697-28-1 4-Bromo-3-Methylbenzoic Acid
- Fluralaner-017
- Fluralaner Impurity 37
- 7697-28-1
- BrC6H3CH3CO2H
- C8
- Carbonyl Compounds
- Carboxylic Acids
- Building Blocks
- Organic Building Blocks
- blocks
- Bromides
- Carboxes
- Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
- Benzoic acid
- Organic acids
- Acids & Esters
- Bromine Compounds
- C8
- Carbonyl Compounds
- Carboxylic Acids
