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GLP-1 (7-37)

GLP-1 (7-37) Struktur
106612-94-6
CAS-Nr.
106612-94-6
Englisch Name:
GLP-1 (7-37)
Synonyma:
Tglp-1;GLP-1, 7-37;HuMan GLP-1;Glp-I (7-37);insulinotropin;GLP-1(7-37), >98%;Human GLP-1 (7-37);GLP-1 acetate salt;GLP-1 (7-37) (HUMAN);GLP-1(7-37) impurity
CBNumber:
CB1445727
Summenformel:
C151H228N40O47
Molgewicht:
3355.67
MOL-Datei:
106612-94-6.mol

GLP-1 (7-37) Eigenschaften

Dichte
1.48±0.1 g/cm3(Predicted)
storage temp. 
−20°C
L?slichkeit
Water:30.0(Max Conc. mg/mL);8.34(Max Conc. mM)
Aggregatzustand
Lyophilized powder
Farbe
White to off-white
Wasserl?slichkeit
Soluble in water at 2mg/ml
Sequenz
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH
CAS Datenbank
106612-94-6

Sicherheit

S-S?tze: 22-24/25
WGK Germany  3

GLP-1 (7-37) Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Beschreibung

GLP-1 (7-37) is an endogenous truncated form of GLP-1 that arises from proglucagon processing in intestinal endocrine L cells, GLP-1 (7-37) acts as a GLP-1 receptor agonist and is an insulinotropic hormone that augments glucose induced insulin secretion. GLP-1 (7-37) and derivatives GLP-1 (9-37) and GLP-1 (28-37) can reduce plaque inflammation and increase phenotypic characteristics of plaque stability in a murine model of atherosclerosis.

Verwenden

Glucagon-Like Peptide 1 Fragment 7-37 human has been used:
  • as a positive control for insulin secretion of pancreatic islets
  • to test its effect on insulin response in horse islets
  • in combination with mesenchymal stem cells (MSCs) test its protective effects in myocardial infarction

Allgemeine Beschreibung

Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) is an amino-truncated form of GLP-1.

Biochem/physiol Actions

Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) interacts with the GLP-1 receptor (GLP-1r). It mediates insulin release by stimulating the cyclic AMP accumulation in islet cells GLP-l(7-37) is a potential therapeutic agent due to its insulin-secretagogue functionality.

GLP-1 (7-37) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


GLP-1 (7-37) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 187)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Cellmano Biotech Limited
0551-65326643 18156095617
info@cellmano.com China 1000 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823
admin@guyunchem.com China 615 58
Wuhan senwayer century chemical Co.,Ltd
+undefined-27-86652399 +undefined13627115097
market02@senwayer.com China 902 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 10986 58
Shanghai Getian Industrial Co., LTD
+86-15373193816 +86-15373193816
mike@ge-tian.com China 269 58
Alpha Biopharmaceuticals Co., Ltd
+86-15542445688
sales@alabiochem.com China 888 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21639 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9218 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32820 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29886 58

  • Insulinotropin (human)
  • Peptide GLP-1 (human glucose-lowering peptide-1)
  • Glp-I (7-37)
  • Glucagon like peptide I (7-37)
  • Glucagon-related peptide (oncorhynchus kisutch), 3-L-glutamic acid-6-L-phenylalanine-9-L-aspartic acid-12-L-serine-15-L-glutamic acid-16-glycine-21-L-isoleucine-24-L-alanine-27-L-valine-28-L-lysine-31-glycine-
  • Tglp-1
  • GLP-1, 7-37
  • Preproglucagon 78-108
  • GLP-1 (7-37) (huMan, bovine, guinea pig, Mouse, rat) Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucag
  • 7-37-Glucagon-like peptide I (human)
  • Human GLP-1 (7-37)
  • insulinotropin
  • GLP-1, 7-37, Preproglucagon 78-108
  • Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)
  • Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)
  • HuMan GLP-1
  • 7-37-Glucagon-likepeptide
  • H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH acetate salt
  • GLP-1 (7-37) Acetate | Glucagon-Like Peptide 1
  • l-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alany
  • PROGLUCAGON (78-108) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • PREPROGLUCAGON 78-108 HUMAN
  • PREPROGLUCAGON (98-128) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • INSULINOTROPIN (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
  • HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
  • GLP-1 (HUMAN, 7-37) (BOVINE, CANINE, RAT, GUINEA PIG)
  • GLP-1 (7-37) (HUMAN)
  • GLP-1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • GLUCAGON-LIKE PEPTIDE 1 (HUMAN, 7-37) (BOVINE, CANINE, RAT, GUINEA PIG)
  • GLUCAGON LIKE PEPTIDE-I (7-37), HUMAN
  • GLUCAGON-LIKE PEPTIDE 1, FRAGMENT 7-37 HUMAN
  • GLUCAGON-LIKE PEPTIDE 1 (7-37)
  • GLUCAGON-LIKE PEPTIDE 1 (7-37) (HUMAN)
  • GLUCAGON-LIKE PEPTIDE 1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • GLP-1(7-38), Insulinotropin
  • Glucagon-Like Peptide (GLP) I (7-37)
  • GLP-1(7-37), >98%
  • GLP-1(7-37),HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG, >98%
  • GLP-1(7-37) impurity
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH USP/EP/BP
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GL...
  • TIANFUCHEM--106612-94-6---H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR- LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-LE-ALA-TRP-LEU-VAL- LYS-GLY-ARG-GLY-OH
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
  • Insulinotropin acetate [GLP-1 (7-37)
  • GLP-1 acetate salt
  • Glucagon-Like Peptide-1 (7-37)|GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat)
  • (5S,11S,14S,17S,20S,23S,26S,29S,32S,35S,38S,41S,44S,50S,53S,56S,59S,62S,65S,68S,71S,74S,77S,80S,86S)-20-((1H-Indol-3-yl)methyl)-86-((S)-2-((S)-2-amino-3-(1H-imidazol-5-yl)propanamido)propanamido)-44-(3-amino-3-oxopropyl)-11,35-bis(4-aminobutyl)-29,77-dibenzyl-26-((S)-sec-butyl)-32,50-bis(2-carboxyethyl)-68-(carboxymethyl)-5-(3-guanidinopropyl)-56-(4-hydroxybenzyl)-74,80-bis((R)-1-hydroxyethyl)-59,62,71-tris(hydroxymethyl)-17,53-diisobutyl-14,65-diisopropyl-23,38,41-trimethyl-4,7,10,13,16,19,22,2
  • 106612-94-6
  • C151H228N40O47
  • peptides pharm
  • peptide
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