1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
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- CAS-Nr.
- 55314-16-4
- Englisch Name:
- 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
- Synonyma:
- 4G-951;Imatinib Impurity 19;Imatinib Impurity 74;Imatinib EP Impurity A;Imatinib USP Impurity A;Nilotinib??Intermediates?B;Imatinib Related Compound A;Imatinib Dimethylamino Impurity;3-Dimethylamino-1-pyridin-3-yl-pr;3-[3-(Dimethylamino)acryloyl]pyridine
- CBNumber:
- CB1406106
- Summenformel:
- C10H12N2O
- Molgewicht:
- 176.22
- MOL-Datei:
- 55314-16-4.mol
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1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Eigenschaften
- Schmelzpunkt:
- 86-88
- Siedepunkt:
- 281.4±36.0 °C(Predicted)
- Dichte
- 1.070±0.06 g/cm3(Predicted)
- Dampfdruck
- 0.049Pa at 20℃
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- Soluble in chloroform and dichloromethane.
- Aggregatzustand
- powder to crystal
- pka
- 6.19±0.70(Predicted)
- Farbe
- Light yellow to Brown
- InChI
- InChI=1S/C10H12N2O/c1-12(2)7-5-10(13)9-4-3-6-11-8-9/h3-8H,1-2H3
- InChIKey
- MZLRFUCMBQWLNV-FNORWQNLSA-N
- SMILES
- C(C1=CC=CN=C1)(=O)C=CN(C)C
- LogP
- 0.26 at 20℃ and pH7.2
- Oberfl?chenspannung
- 71.8mN/m at 1.008g/L and 20℃
- CAS Datenbank
- 55314-16-4(CAS DataBase Reference)
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one can be used in the synthesis of imatinib and nilotinib (AMN107), a compound currently in multiple Phase II/III clinical trials for chronic granulocytic leukaemia. Imatinib, on the other hand, is a cancer growth blocker known as a tyrosine kinase inhibitor (TKI), which is used to treat a wide range of leukaemias, myelodysplastic/myeloproliferative disorders, systemic mastocytosis, eosinophilia syndromes, raised dermal fibrosarcoma and gastrointestinal mesenchymal tumours.
Chemische Eigenschaften
Off-White Solid
Solubility in organics
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one is soluble in Chloroform and Dichloromethane.
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 253)Lieferanten
55314-16-4()Verwandte Suche:
- 2-DiMethylaMino-1-(3-pyridyl)-2-propene-1-one
- 3-[3-(Dimethylamino)acryloyl]pyridine
- 2-(Dimethylamino)ethenyl 3-Pyridyl Ketone
3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one
3-[3-(Dimethylamino)acryloyl]pyridine
- (E)-3-DIMETHYLAMINO-1-PYRIDIN-3-YL-PROPENONE
- 3-diMethylaMino-1-(3-pyridyl)-2-propen-1-one, 3-(N,N-diMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one, 3-(diMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one
- 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one
- (2E)-3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one
- (E)-3-dimethylamino-1-(3-pyridyl)prop-2-en-1-one
- 3-dimethylamino-1-(3-pyridyl)prop-2-en-1-one
- 3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
- 4G-951
- Imatinib Dimethylamino Impurity
- Imatinib USP Impurity A
- 3-(DIMETHYLAMINO)-1-(3-PYRIDINYL)-2-PROPEN-1-ONE
- 1-(3-PYRIDYL)-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE
- 3-(Dimethylamino)-1-pyridin-3-ylprop-2-en-1-one
- 2-propen-1-one,3-（dimethylamino）-1-（3-pyridinyl）
- 3-Dimethylamino-1-(pyridin-3-yl)propenone
- 1-(3-PYRIDYL)-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE 95%
- 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ,97%
- 2-(DiMethylaMino)vinyl 3-Pyridyl Ketone
- Imatinib Related Compound A
- 3-(Dimethylamino)-1-(3-pyridinyl)-2-propene-1-one
- Imatinib Impurity 19
- Imatinib EP Impurity A
- 2-(Dimethylamino)vinyl3-PyridylKetone>
- Imatinib Dimethylamino Impurity Certified Reference Standard
- 2-(Dimethylamino)ethenyl 3-Pyridyl Ketone
- 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ISO 9001：2015 REACH
- Imatinib EP Impurity A (Imatinib Dimethylamino Impurity)
- Nilotinib??Intermediates?B
- 1 - (3-pyridyl) - 3 - (dimethylamino) - 2-propene-1-one
- 3-Dimethylamino-1-pyridin-3-yl-pr
- Imatinib Dimethylamino ImpurityQ: What is
Imatinib Dimethylamino Impurity Q: What is the CAS Number of
Imatinib Dimethylamino Impurity Q: What is the storage condition of
Imatinib Dimethylamino Impurity Q: What are the applications of
Imatinib Dimethylamino Impurity
- 2-(Dimethylamino)vinyl 3-Pyridyl Ketone, ≥ 95.0%
- Imatinib Impurity 74
- 55314-16-4
- Intermediate of Imatinib
- Chemical Amines
- Amines
- Bases & Related Reagents
- Intermediates & Fine Chemicals
- Nucleotides
- Pharmaceuticals
- Heterocycles
- Intermediates
