AC-IETD-AFC Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin is a fluorogenic substrate for caspases -6, -8, and -10. The IETD sequence is based on the procaspase-3 cleavage site. Residues 172-175 of procaspase-3 are cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.
AC-IETD-AFC Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte