1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE
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- CAS-Nr.
- 34880-70-1
- Englisch Name:
- 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE
- Synonyma:
- Methoxytrimethylsilyloxypropene;1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE;1-methoxyprop-1-enoxy(trimethyl)silane;1-(Trimethylsiloxy)-1-methoxy-1-propene;1-Methoxy-1-trimethylsilyloxypropene>Trimethyl(1-methoxy-1-propenyloxy)silane;Methylketene methyl(trimethylsilyl)acetal;1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE 95+%;[(1-METHOXY-1-PROPENYL)OXY]TRIMETHYLSILANE;Silane, [(1-methoxy-1-propenyl)oxy]trimethyl-
- CBNumber:
- CB1383968
- Summenformel:
- C7H16O2Si
- Molgewicht:
- 160.29
- MOL-Datei:
- 34880-70-1.mol
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1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE Eigenschaften
- Siedepunkt:
- 52 °C / 27mmHg
- Dichte
- 0.87
- Brechungsindex
- 1.4130-1.4160
- storage temp.
- 0-10°C
- Aggregatzustand
- clear liquid
- Farbe
- Colorless to Almost colorless
- Wichte
- 0.87
- CAS Datenbank
- 34880-70-1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| RIDADR |
1993 |
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| HazardClass |
3 |
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| PackingGroup |
III |
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| HS Code |
2931900090 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H226 |
Flüssigkeit und Dampf entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 3 |
Warnung |
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| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P210 |
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P233 |
Beh?lter dicht verschlossen halten. |
| P240 |
Beh?lter und zu befüllende Anlage erden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
1-Methoxy-1-(trimethylsilyloxy)propene is used to reactive nucleophile in Mukaiyama-type aldol reactions with aldehydes, imines, acetals,
dialkoxycarbenium ions, and orthoesters; Michael-type additions to α,β-unsaturated carbonyl compounds; substitution reactions with allylic alcohols and esters; acylations; aminations; hydroxylations; and
pericyclic reactions; silylating agent.
synthetische
since the first preparation of a ketene trialkylsilyl acetal by Petrov in 1959 by the reaction
of triethylsilane and methyl acrylate, several alternative pathways have been explored. Ainsworth and coworkers prepared 1-methoxy-1-(trimethylsilyloxy)propene in 90% yield by deprotonation of methyl propionate
with Lithium Diisopropylamide at -78 °C followed by addition of Chlorotrimethylsilane. Reaction of the
lithium enolate of methyl acetate with TMS-Cl provides 65% O-silylated and 35% C-silylated products (eq 1).
Substitution on the alcohol portion of the ester favors C-silylation while substitution on the α-carbon favors O-silylation. An increase in the steric bulk of the silylating agent (e.g. use of t-Butyldimethylchlorosilane) results
in significantly more O-silylation.
1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 51)Lieferanten
34880-70-1()Verwandte Suche:
- 1-(Trimethylsiloxy)-1-methoxy-1-propene
- Methylketene methyl(trimethylsilyl)acetal
- Trimethyl(1-methoxy-1-propenyloxy)silane
- (E)-((1-Methoxyprop-1-en-1-yl)oxy)triMethylsilane
- 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE
- [(1-METHOXY-1-PROPENYL)OXY]TRIMETHYLSILANE
- Methoxytrimethylsilyloxypropene
- 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE 95+%
- 1-Methoxy-1-trimethylsilyloxypropene>
- Silane, [(1-methoxy-1-propenyl)oxy]trimethyl-
- 1-methoxyprop-1-enoxy(trimethyl)silane
- 34880-70-1
- Protection & Derivatization Reagents (for Synthesis)
- Monoalkoxysilanes
- Si-O Compounds
- Si (Classes of Silicon Compounds)
- Vinylsilanes, Allylsilanes
- Monoalkoxysilanes
- Protection & Derivatization Reagents (for Synthesis)
- Si (Classes of Silicon Compounds)
- Si-O Compounds
- Synthetic Organic Chemistry
- Vinylsilanes, Allylsilanes
