2,2,6,6-Tetramethylheptan-3,5-dion Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S22:Staub nicht einatmen.
Chemische Eigenschaften
CLEAR COLOURLESS TO SLIGHTLY YELLOW LIQUID
Verwenden
2,2,6,6-tetramethyl-3,5-heptanedione was used in the synthesis of α-aryl-β-diketones1 and dicyanamidobenzene-bridge diruthenium complex.
Definition
2,2,6,6-Tetramethyl-3,5-heptanedioneis a stable, anhydrous reagent. It undergoes O-additions and C-additions. In various reactions, it acts as an air-stable ligand for metal catalysts. Furthermore, it serves as a substrate for heterocycles.
Allgemeine Beschreibung
Acylation, a replacement to silylation, allows the conversion of compounds that consist of active hydrogens (-OH, -SH and -NH) into esters, thioesters, and amides via the action of a carboxylic acid or derivative. The carbonyl group adjacent to the halogenated carbons is known to improve the electron capture detector (ECD) response. Acylation has several advantages:
- It enhances the stability of compounds by protecting unstable groups.
- It may confer volatility on substances like carbohydrates or amino acids, that have several polar groups that they are non-volatile and usually decompose on heating.
- It facilitates the separations not possible with underivatized compounds.
- Compounds are detectable at very low levels with an ECD.
2,2,6,6-Tetramethyl-3,5-heptanedione is a reagent used to form fragmentation-directing derivatives for GC/MS analysis.
Synthese
Methyl pivalate and formamide could be used as starting materials to synthesize 2,2,6,6-Tetramethyl-3,5-heptanedione.
2,2,6,6-Tetramethylheptan-3,5-dion Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Natriumhydrid
Ethanol
N,N-Dimethylformamid
3,3-Dimethylbutanon
Tetrahydrofuran
Diethylether
Ethylacetat
Methylpivalat
Hydrogenchlorid
4-Heptyn-3-one, 2,2,6,6-tetramethyl-
Benzenemethanamine, N-(1,2,2-trimethylpropylidene)-
Dipivaloylamine
2,2-Dimethylpropanoic acid phenyl ester
Propanamide,2,2-dimethyl-N-(phenylmethyl)-
2,3,3-TRIMETHYL-2-BUTANOL
8-Hydroxychinolin
Downstream Produkte
N,N-DIPHENYLQUINACRIDONE
2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO POTASSIUM
3,5-Heptanedione, 4-bromo-2,2,6,6-tetramethyl-
