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R-IMPP

R-IMPP Struktur
2133832-83-2
CAS-Nr.
2133832-83-2
Englisch Name:
R-IMPP
Synonyma:
R-IMPP;PF-00932239 (R-IMPP);Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-;(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide;Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases
CBNumber:
CB13155117
Summenformel:
C24H27N3O2
Molgewicht:
389.49
MOL-Datei:
2133832-83-2.mol

R-IMPP Eigenschaften

Siedepunkt:
594.4±50.0 °C(Predicted)
Dichte
1.186±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 1 mg/ml; DMSO: 10 mg/ml
Aggregatzustand
A crystalline solid
pka
9.14±0.10(Predicted)
Farbe
Light yellow to yellow

Sicherheit

R-IMPP Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC50 = 4.8 μM). It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels. (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.

R-IMPP Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


R-IMPP Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 36)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32956 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33338 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58
MedChemexpress LLC 021-58955995
sales@medchemexpress.cn United States 4861 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
klq@cw-bio.com China 5931 55

  • R-IMPP
  • Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-
  • PF-00932239 (R-IMPP)
  • (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide
  • Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases
  • 2133832-83-2
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