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(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Struktur
475473-26-8
CAS-Nr.
475473-26-8
Englisch Name:
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
Synonyma:
CORM-3;CORM-3, 10 mM in DMSO;Carbon monoxide releasing molecule 3;Tricarbonylchloro(glycinato)ruthenium;Tricarbonylchloro(glycinato)ruthenium (II);(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium;(OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium;Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-;inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR)
CBNumber:
CB12717709
Summenformel:
C5H3ClNO5Ru
Molgewicht:
293.6
MOL-Datei:
475473-26-8.mol

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Eigenschaften

storage temp. 
-20°C
L?slichkeit
H2O: soluble20mg/mL, clear
Aggregatzustand
powder
Farbe
light yellow to dark yellow
Wasserl?slichkeit
Soluble to 100 mM in water

Sicherheit

WGK Germany  3

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CORM-3 (carbon monoxide (CO) releasing molecule-3) has been used to study its effect on NLRP3 (leucine-rich-repeat-containing receptor, pyrin-domain-containing 3) inflammasome activation via glycolysis in macrophages and also on hyperglycemia-induced IL-1β (interleukin-1 β) production. It has also been used to study its protective function against H2O2-induced apoptosis using primary rabbit lens epithelial cells.

Biochem/physiol Actions

CORM-3 is a water-soluble carbon monoxide (CO) releasing molecule that can be used to study the effects of CO on cellular systems. Carbon monoxide (CO), produced during the degradation of heme by the enzyme heme oxygenase, has recently been found to be an important gaseous signaling mediator in mammalian cells CORM-3 has been shown to have anti-inflammatory and cardioprotective activity.

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
  • CORM-3
  • Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-
  • Carbon monoxide releasing molecule 3
  • Tricarbonylchloro(glycinato)ruthenium (II)
  • Tricarbonylchloro(glycinato)ruthenium
  • inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR)
  • (OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium
  • CORM-3, 10 mM in DMSO
  • 475473-26-8
  • C5H4ClNO5Ru
  • Inhibitors
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