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CYP3cide

CYP3cide Struktur
1390637-82-7
CAS-Nr.
1390637-82-7
Englisch Name:
CYP3cide
Synonyma:
CYP3cide;PF-4981517;PF-04981517;CYP3cide USP/EP/BP;CYP3cide, PF-04981517;CYP3cide DISCONTINUED;PF 04981517 - CYP3cide | PF 4981517;1-methyl-3-[1-methyl-5-(4-methylphenyl)pyrazol-4-yl]-4-[(3S)-3-piperidin-1-ylpyrrolidin-1-yl]pyrazolo[3,4-d]pyrimidine;1-Methyl-3-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-4-[(3S)-3-piperidin-1-ylpyrrolidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine;1H-Pyrazolo[3,4-d]pyrimidine, 1-methyl-3-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-4-[(3S)-3-(1-piperidinyl)-1-pyrrolidinyl]-
CBNumber:
CB12620906
Summenformel:
C26H32N8
Molgewicht:
456.59
MOL-Datei:
1390637-82-7.mol

CYP3cide Eigenschaften

Siedepunkt:
630.2±55.0 °C(Predicted)
Dichte
1.34±0.1 g/cm3(Predicted)
storage temp. 
room temp
L?slichkeit
Soluble in DMSO
Aggregatzustand
powder
pka
8.88±0.20(Predicted)
Farbe
white to beige

Sicherheit

WGK Germany  3

CYP3cide Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White to Off-White Solid

Verwenden

CYP3cide is a potent and selective time dependent inactivator of Cytochrome P450 3A4 (CYP3A4). CYP3A4 is an important enzymes involved in the metabolism of xenobiotics in the human body and constitutes to about a quarter of all CYPs in the human body. CYP3cide provides a useful in vitro tool in defining the individual roles of CYP3A4 versus CYP3A5 in the metabolism of drugs.

Biochem/physiol Actions

CYP3cide is a mechanism-based inhibitor of cytochrome P4503A4 that can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug metabolism. The IC50 values for inhibition of Midazolam 1′-Hydroxylase activity of recombinant CYP3A4 and CYP3A5 by CYP3cide are 0.3 and 17 mM, respectively.

CYP3cide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CYP3cide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 73)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29815 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32070 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 23125 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8467 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 94657 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826
market@aladdin-e.com China 25003 65

1390637-82-7()Verwandte Suche:


  • CYP3cide
  • PF-04981517
  • PF-4981517
  • 1H-Pyrazolo[3,4-d]pyrimidine, 1-methyl-3-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-4-[(3S)-3-(1-piperidinyl)-1-pyrrolidinyl]-
  • 1-Methyl-3-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-4-[(3S)-3-piperidin-1-ylpyrrolidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
  • 1-methyl-3-[1-methyl-5-(4-methylphenyl)pyrazol-4-yl]-4-[(3S)-3-piperidin-1-ylpyrrolidin-1-yl]pyrazolo[3,4-d]pyrimidine
  • PF 04981517 - CYP3cide | PF 4981517
  • CYP3cide, PF-04981517
  • CYP3cide USP/EP/BP
  • CYP3cide DISCONTINUED
  • 1390637-82-7
  • C26H32N8
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pfizer Compounds
  • Pharmaceuticals
  • Inhibitor
  • Heterocycles, Inhibitors, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
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