GSK-3 Inhibitor IX, Control, MeBIO Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
A cell-permeable N-methylated analog of GSK-3 Inhibitor IX, BIO (Cat. No. 361550) that serves as an inactive control for Cdk1/cyclin B, Cdk5/p25, and GSK-3α/β (IC
50 >92 μM for Cdk1/cyclin B, >100 μM for Cdk5/p25, and GSK-3α/β). Acts as a potent ligand for aryl hydrocarbon receptor (AhR; EC
50 = 20 nM and 93 nM for yeast and hepatoma reporter systems, respectively) and displays antiproliferative properties.
Biochem/physiol Actions
Cell permeable: yes
GSK-3 Inhibitor IX, Control, MeBIO Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte