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ZONIPORIDE DIHYDROCHLORIDE

ZONIPORIDE DIHYDROCHLORIDE Struktur
241800-97-5
CAS-Nr.
241800-97-5
Englisch Name:
ZONIPORIDE DIHYDROCHLORIDE
Synonyma:
Zoniporide dihydroch;ZONIPORIDE DIHYDROCHLORIDE;[1-(quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine hydrochloride;[1-(QUINOLIN-5-YL)-5-CYCLOPROPYL-1H-PYRAZOLE-4-CARBONYL]GUANIDINE DIHYDROCHLORIDE;5-cyclopropyl-N-(diaminomethylidene)-1-quinolin-5-ylpyrazole-4-carboxamide:hydrochloride
CBNumber:
CB12453438
Summenformel:
C17H17ClN6O
Molgewicht:
356.81
MOL-Datei:
241800-97-5.mol

ZONIPORIDE DIHYDROCHLORIDE Eigenschaften

storage temp. 
Desiccate at -20°C
L?slichkeit
≤1mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
Stabilit?t:
Hygroscopic

Sicherheit

ZONIPORIDE DIHYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

The sodium-hydrogen exchanger isoform-1 (NHE-1) is the most predominant isoform of the Na+/H+ exchanger and is expressed in the heart where it contributes to cardiomyocyte pH homeostasis. It plays an important role in the myocardial response to ischemia-reperfusion. Zoniporide inhibits human NHE-1 with an IC50 value of 14 nM, displaying greater than 150-fold selectivity over other NHE isoforms. It has been shown to reduce infarct size in a rabbit myocardial ischemia-reperfusion model without adversely affecting hemodynamics or cardiac function. In isolated heart, zoniporide reduced infarct size with an EC50 value of 0.25 nM.

ZONIPORIDE DIHYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ZONIPORIDE DIHYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 21)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32002 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15839 69
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11217 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8140 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44918 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8617 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223;
psaitong@jm-bio.com China 29774 58

  • [1-(QUINOLIN-5-YL)-5-CYCLOPROPYL-1H-PYRAZOLE-4-CARBONYL]GUANIDINE DIHYDROCHLORIDE
  • ZONIPORIDE DIHYDROCHLORIDE
  • [1-(quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine hydrochloride
  • 5-cyclopropyl-N-(diaminomethylidene)-1-quinolin-5-ylpyrazole-4-carboxamide:hydrochloride
  • Zoniporide dihydroch
  • 241800-97-5
  • C17H16N6O2HCl
  • C17H16N6OHCl
  • C17H16N6OClH
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