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T 98475

T 98475 Struktur
192887-28-8
CAS-Nr.
192887-28-8
Englisch Name:
T 98475
Synonyma:
T 98475;3-[(BENZYL-METHYL-AMINO)-METHYL]-7-(2,6-DIFLUORO-BENZYL)-2-(4-ISOBUTYRYLAMINO-PHENYL)-4-OXO-4,7-DIHYDRO-THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID ISOPROPYL ESTER;THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID, 7-[(2,6-DIFLUOROPHENYL)METHYL]-4,7-DIHYDRO-2-[4-[(2-METHYL-1-OXOPROPYL)AMINO]PHENYL]-3-[[METHYL(PHENYLMETHYL)AMINO]METHYL]-4-OXO-, 1-METHYL;7-[(2,6-DIFLUOROPHENYL)METHYL]-4,7-DIHYDRO-2-[4-[(2-METHYL-1-OXOPROPYL)AMINO]PHENYL]-3-[[METHYL(PHENYLMETHYL)AMINO]METHYL]-4-OXO-THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID 1-METHYLETHYL ESTER;THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID, 7-[(2,6-DIFLUOROPHENYL)METHYL]-4,7-DIHYDRO-2-[4-[(2-METHYL-1-OXOPROPYL)AMINO]PHENYL]-3-[[METHYL(PHENYLMETHYL)AMINO]METHYL]-4-OXO-, 1-METHYLETHYL ESTER
CBNumber:
CB12453423
Summenformel:
C37H37F2N3O4S
Molgewicht:
0
MOL-Datei:
192887-28-8.mol

T 98475 Eigenschaften

Schmelzpunkt:
168-170 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
storage temp. 
Desiccate at +4°C

Sicherheit

T 98475 Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivit?t

Potent, orally active and non-peptide gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist (IC 50 values are 0.2, 4.0 and 60 nM for human, monkey and rat GnRH receptors respectively). Inhibits LH release in vitro (IC 50 = 100 nM) and reduces plasma LH concentration in castrated male cynomolgus monkeys.

T 98475 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

T 98475 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 14)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
  • 3-[(BENZYL-METHYL-AMINO)-METHYL]-7-(2,6-DIFLUORO-BENZYL)-2-(4-ISOBUTYRYLAMINO-PHENYL)-4-OXO-4,7-DIHYDRO-THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID ISOPROPYL ESTER
  • 7-[(2,6-DIFLUOROPHENYL)METHYL]-4,7-DIHYDRO-2-[4-[(2-METHYL-1-OXOPROPYL)AMINO]PHENYL]-3-[[METHYL(PHENYLMETHYL)AMINO]METHYL]-4-OXO-THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID 1-METHYLETHYL ESTER
  • T 98475
  • THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID, 7-[(2,6-DIFLUOROPHENYL)METHYL]-4,7-DIHYDRO-2-[4-[(2-METHYL-1-OXOPROPYL)AMINO]PHENYL]-3-[[METHYL(PHENYLMETHYL)AMINO]METHYL]-4-OXO-, 1-METHYLETHYL ESTER
  • THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID, 7-[(2,6-DIFLUOROPHENYL)METHYL]-4,7-DIHYDRO-2-[4-[(2-METHYL-1-OXOPROPYL)AMINO]PHENYL]-3-[[METHYL(PHENYLMETHYL)AMINO]METHYL]-4-OXO-, 1-METHYL
  • 192887-28-8
  • C37H37F2N3O4S
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