Spirolaxin Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Spirolaxine is a long-chain phthalide produced by the fungus
S. laxum that has antibacterial properties. Spirolaxine is a potent anti-
H. pylori agent (MIC = 0.2 μg/cm
3) with weak activity against
E. coli. Spirolaxine (1-40 μM) inhibits proliferation of endothelial (BMEC, HUVEC) and tumor (LoVo, HL-60) cells in culture.
B. megaterium and
C. echinulate produce hydroxylated metabolites of spirolaxine when given spirolaxine as a substrate.
Verwenden
Spirolaxine is a bioactive undecaketide fungal metabolite found in Sporotrichum laxum ATCC 15155. Spirolaxine exhibits anti-Helicobacter pylori property.
Spirolaxin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte