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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Struktur
103878-83-7
CAS-Nr.
103878-83-7
Englisch Name:
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Synonyma:
TeMpiuM;Ro 19-6327/001;JMFKTFLARGGXCC-UHFFFAOYSA-N;N-(2-Aminoethyl)-5-chlor-2-pyridincarbox;N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid;N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride;2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-, Monohydrochloride;ichemia,Lazabemide,DOPAC,MAO,radical generation,Ro 19-6327,disease,alzheimer′s,Inhibitor,inhibit,Lazabemide hydrochloride,Monoamine Oxidase,smoking cessation,parkinson
CBNumber:
CB11448718
Summenformel:
C8H10ClN3O.HCl
Molgewicht:
0
MOL-Datei:
103878-83-7.mol

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Eigenschaften

Schmelzpunkt:
193-195°
storage temp. 
Desiccate at RT
L?slichkeit
Soluble to 100 mM in water and to 100 mM in DMSO
Aggregatzustand
Powder
pka
8.9(at 25℃)

Sicherheit

Toxizit?t LD50 orally in mice: 1000-2000 mg/kg (Imhof, Kyburz, 1986)

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Treatment of Alzheimer’s disease.

Trademarks

Tempium (Hoffmann-LaRoche).

Biologische Aktivit?t

Selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC 50 values are 0.03 and > 100 μ M for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC 50 values are 86, 123 and > 500 μ M for noradrenalin, serotonin and dopamine uptake respectively).

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 24)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32079 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30241 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38469 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43340 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203
 info@chemextension.com China 42056 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Beijing HuaMeiHuLiBiological Chemical 010-56205725
waley188@sohu.com China 12335 58
Shanghai JiYi Biotechnology Co. Ltd. 13621943973
 sales@shjiyipharmatech.com China 1166 55

103878-83-7()Verwandte Suche:

  • N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
  • 2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-, Monohydrochloride
  • Ro 19-6327/001
  • TeMpiuM
  • N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride
  • JMFKTFLARGGXCC-UHFFFAOYSA-N
  • N-(2-Aminoethyl)-5-chlor-2-pyridincarbox
  • ichemia,Lazabemide,DOPAC,MAO,radical generation,Ro 19-6327,disease,alzheimer′s,Inhibitor,inhibit,Lazabemide hydrochloride,Monoamine Oxidase,smoking cessation,parkinson
  • 103878-83-7
  • C8H10ClN3OHCl
  • Monoamine Oxidase
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