macbecin I Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Macbecin I is an ansamycin antibiotic inhibitor of Hsp90 activity.

Biologische Aktivit?t

Ansamycin antibiotic compound that inhibits Hsp90 activity (IC 50 = 2 μ M) by binding to the ATP-binding site. Exhibits antitumor and cytocidal activities (IC 50 ~ 0.4 μ M) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Displays higher affinity and potency than geldanamycin (9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-carbamate ).

macbecin I Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

macbecin I Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24644	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58
ApexBio Technology	--	sales@apexbt.com	United States	6251	58

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• macbecin I
• (6S,15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methylgeldanamycin
• (15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin
• Geldanamycin, 6,17-didemethoxy-15-methoxy-6-methyl-11-O-methyl-, (15R)-
• Macbecin
• 73341-72-7