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ent-idoxuridine

ent-idoxuridine Struktur
162239-35-2
CAS-Nr.
162239-35-2
Englisch Name:
ent-idoxuridine
Synonyma:
ent-Idoxuridine;Idoxuridine Enantiomer;Idoxuridine Impurity 1;2'-Deoxy-L-5-iodouridine;5-Iodo-2'-deoxy-L-uridine;1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-iodo-2,4(1H,3H)-pyriMidinedione;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-iodo-
CBNumber:
CB11269894
Summenformel:
C9H11IN2O5
Molgewicht:
354.1
MOL-Datei:
162239-35-2.mol

ent-idoxuridine Eigenschaften

InChI
InChI=1/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5?,6-,7-/s3
InChIKey
XQFRJNBWHJMXHO-WGPDPFDPNA-N
SMILES
N1C(=O)C(I)=CN([C@@H]2CC(O)[C@H](CO)O2)C1=O |&1:7,11,r|

Sicherheit

ent-idoxuridine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ent-Idoxuridine, also known as 5-iodo-2'-deoxyuridine, is a cytosolic DNA synthesis inhibitor that acts by blocking the conversion of deoxycytidine to deoxyadenosine through the inhibition of the enzyme deoxycytidine kinase. As an enantiomer of idoxuridine, it shares the exact mechanism of action. Notably, ent-idoxuridine is resistant to exonucleases and has demonstrated effectiveness in treating immunodeficiency caused by HIV.

Verwenden

The enantiomer of Idoxuridine (I205750). Antitumor nucleoside enantiomer thymidine kinase used as potential antiviral agents.

ent-idoxuridine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ent-idoxuridine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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162239-35-2()Verwandte Suche:

  • 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-iodo-
  • ent-Idoxuridine
  • 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-iodo-2,4(1H,3H)-pyriMidinedione
  • 2'-Deoxy-L-5-iodouridine
  • 5-Iodo-2'-deoxy-L-uridine
  • Idoxuridine Impurity 1
  • Idoxuridine Enantiomer
  • 162239-35-2
  • Bases & Related Reagents
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
  • Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
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