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GLY-ARG-GLY-ASP-SER-PRO-LYS

GLY-ARG-GLY-ASP-SER-PRO-LYS Struktur
111119-28-9
CAS-Nr.
111119-28-9
Englisch Name:
GLY-ARG-GLY-ASP-SER-PRO-LYS
Synonyma:
GRGDSPK;EMD 56574;GRGDSPK (EMD 56574);GLY-ARG-GLY-ASP-SER-PRO-LYS;H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH;GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE;GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE;Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC);glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
CBNumber:
CB1123649
Summenformel:
C28H49N11O11
Molgewicht:
715.76
MOL-Datei:
111119-28-9.mol

GLY-ARG-GLY-ASP-SER-PRO-LYS Eigenschaften

Dichte
1.59±0.1 g/cm3(Predicted)
storage temp. 
-20°C
pka
3.60±0.21(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white

Sicherheit

WGK Germany  3

GLY-ARG-GLY-ASP-SER-PRO-LYS Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Gly-Arg-Gly-Asp-Ser-Pro-Lys (RGD peptide) has been used-
  • as a blocking peptide to inhibit integrin-fibronectin binding
  • in adhesion assay performed on porcine trophectoderm to study the influence of TGFβ (transforming growth factor) on cell adhesion
  • for incubation of MC3T3-E1 osteoblast cells to determine its effect on cell adhesion measured by AFM (atomic force microscopy)
  • for the preparation of RGD.Flt23k.NR nanoparticles
  • to determine the involvement of RGD-integrin bonding in cell adhesion process

Allgemeine Beschreibung

Gly-Arg-Gly-Asp-Ser-Pro-Lys is a RGD peptide. Naturally occurring RGD peptides, present in the ECM (extracellalar matrix) proteins, are involved in facilitating integrin-mediated cell adhesion to matrix proteins. RGD peptide is present as repeats in cell-adhesion protein, such as fibronectin and vitronectin. This tripeptide is recognized by cells by specific integrins (e.g. β1 , β3 , and β5 subunits), present on the cell surface and associated with the actin filament via the FA (focal adhesion)-complex.

Biochem/physiol Actions

Fibronectin analog that binds to integrins.

GLY-ARG-GLY-ASP-SER-PRO-LYS Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

GLY-ARG-GLY-ASP-SER-PRO-LYS Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 75)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30239 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
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BOC Sciences 		16314854226; +16314854226
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Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
Chengdu Youngshe Chemical Co., Ltd. 		+8618108235634
 Cecilia@youngshechem.com China 2345 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Hebei Miaoyin Technology Co.,Ltd 		+86-17367732028 +86-17367732028
 kathy@hbyinsheng.com China 3512 58
Nanjing TGpeptide 		+86-13347807150 +86-13347807150
 support@tgpeptide.com China 3279 58
Zhejiang Hangyu API Co., Ltd 		+8617531972939
 anna@api-made.com China 2943 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
  • H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH
  • GRGDSPK
  • GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE
  • GLY-ARG-GLY-ASP-SER-PRO-LYS
  • GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE
  • glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine
  • EMD 56574
  • L-Lysine, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-
  • Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC)
  • Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
  • GRGDSPK (EMD 56574)
  • 111119-28-9
  • C28H49N11O11
  • Extracellular Matrix
  • Extracellular Matrix Peptides and Proteins
  • Cytoskeleton and Extracellular Matrix
  • Cell Signaling and Neuroscience
  • BioChemical
  • Cell Biology
  • peptide
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