Sildenafil Chlorosulfonyl
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- CAS-Nr.
- 139756-22-2
- Englisch Name:
- Sildenafil Chlorosulfonyl
- Synonyma:
- Sildenafil Impurity 7;Methisosildenafil-004;Sildenafil intermediate;Sildenafil Chlorosulfone;Sildenafil chlorosulfonyl;Methisosildenafil Impurity 33;Sildenafil Chlorosulfone IMpurity;Sildenafil Chlorosulfonyl IMpurity;5-(5-CHLORO SULFONYL-2-ETHOXY PHENYL)-1-;4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro
- CBNumber:
- CB11175931
- Summenformel:
- C17H19ClN4O4S
- Molgewicht:
- 410.88
- MOL-Datei:
- 139756-22-2.mol
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Sildenafil Chlorosulfonyl Eigenschaften
- Schmelzpunkt:
- 180-182°C
- Dichte
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- Chloroform (Slightly), Methanol (Slightly, Heated)
- Aggregatzustand
- Solid
- pka
- 9.87±0.20(Predicted)
- Farbe
- White to Pale Beige
- Stabilit?t:
- Moisture Sensitive
- InChI
- InChI=1S/C17H19ClN4O4S/c1-4-6-12-14-15(22(3)21-12)17(23)20-16(19-14)11-9-10(27(18,24)25)7-8-13(11)26-5-2/h7-9H,4-6H2,1-3H3,(H,19,20,23)
- InChIKey
- RVVOSOSBFSYZDM-UHFFFAOYSA-N
- SMILES
- C1(S(Cl)(=O)=O)=CC=C(OCC)C(C2NC(=O)C3N(C)N=C(CCC)C=3N=2)=C1
- CAS Datenbank
- 139756-22-2
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H314 |
Verursacht schwere Ver?tzungen der Haut und schwere Augensch?den. |
?tzwirkung auf die Haut |
Kategorie 1B |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P330+P331 |
BEI VERSCHLUCKEN: Mund ausspülen. KEIN Erbrechen herbeiführen. |
| P303+P361+P353 |
BEI BERüHRUNG MIT DER HAUT (oder dem Haar): Alle kontaminierten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen oder duschen. |
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Sildenafil Chlorosulfonyl Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor sildenafil. It is also a potential impurity found in commercial preparations of sildenafil.
Chemische Eigenschaften
Off-White Solid
Verwenden
The compound Sildenafil Chlorosulfonyl Impurity (139756-22-2) is a derivative of Sildenafil. It is widely used in the treatment of pulmonary hypertension as it is capable of inhibiting cGMP and acts as a potent selective inhibitor of PDE5.
Sildenafil Chlorosulfonyl Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Sildenafil Chlorosulfonyl Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 159)Lieferanten
139756-22-2()Verwandte Suche:
- 3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1 H-pyrazolo-(4-3-d)-pyrimidine-5
- 3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxy-benzenesulfonyl Chloride
- 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
- 5-(5-CHLOROSULFONYL-2-ETHOXY PHENYL)-1-METHYL-3-N-PROPYL-1
- Sildenafil Chlorosulfonyl IMpurity
- 4-Ethoxy-3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyriMidin-5-yl)benzene-1-sulfonyl chloride
- Sildenafil Chlorosulfone IMpurity
- 4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo-[4,3-d]pyrimidin-5-yl)benzene-1-sulfo
- 4-Ethoxy-3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzene-1-sulfonyl chloride
- Sildenafil intermediate
- 4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)
- 4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo-[4,3-d]pyrimidin-5-yl)benzene-1-su
- Sildenafil Impurity 7
- Methisosildenafil-004
- 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazole[4,3-d]pyrimidine-7-one
- Sildenafil impurity 33/Sildenafil Chlorosulfonyl/Sildenafil Chlorosulfone Impurity/5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazole[4,3-d]pyrimidine-7-one
- 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro
- 5-(5-CHLORO SULFONYL-2-ETHOXY PHENYL)-1-
- 5-(5-CHLORO SULFONYL-2-ETHOXY PHENYL)-1- METHYL-3-PROPYL-1 6-DIHYDRO-7H-PYRAZOL O-(4 3-D)PYRIMIDINE-7-ONE
- Methisosildenafil Impurity 33
- Benzenesulfonyl chloride, 3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxy-
- Demethylpiperazinyl sildenafil sulfonyl chloride
- 4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonyl chloride
- 5-(5-CHLORO SULFONYL-2-ETHOXYPHENYL)-1-METHYL-3-N-PROPYL-1,6-DIHYDRO-7H-PYRAZOLO-[4,3,D]-PYRIMIDINE-7-ONE
- 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-Chemicalbookpropyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
- 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-di...
- Sildenafil Chlorosulfone
- Sildenafil chlorosulfonyl
- 4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo4,3-dpyrimidin-5-yl)benzene-1-sulfonyl chloride
- 4-Ethoxy-3-(1-methy1-7-oxo~3-propy1-6,7-diliydro-lH-pyrazolo[4,3-d]pyrimidin-5-yl)benzene-1-suIfonyl cliloride
- Sildenafil Chlorosulfone Impurity / Sildenafil Chlorosulfone / Sildenafil Chlorosulfonyl Impurity
- 139756-22-2
- Bases & Related Reagents
- Nucleotides
- Sulfonyl Chlorides
