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RG108

RG108 Struktur
48208-26-0
CAS-Nr.
48208-26-0
Englisch Name:
RG108
Synonyma:
108;R 108;CS-1518;RG108 >98%;RG108/RG-108;RG108 USP/EP/BP;N-Phthalyl-L-tryptophan;N-Phthaloyl-L-tryptophan;N-Phthalyl-L-tryptophan>N-phthalimide-L-tryptophan
CBNumber:
CB0972112
Summenformel:
C19H14N2O4
Molgewicht:
334.33
MOL-Datei:
48208-26-0.mol

RG108 Eigenschaften

Schmelzpunkt:
192-194℃
Siedepunkt:
606.0±50.0 °C(Predicted)
Dichte
1.502±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
DMSO: >10mg/mL
pka
3.62±0.10(Predicted)
Aggregatzustand
powder
Farbe
yellow
Sensitive 
Light Sensitive
Stabilit?t:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
CAS Datenbank
48208-26-0

Sicherheit

WGK Germany  3
HS Code  2933.99.9701

RG108 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

RG108 has been used:
  • in reprogramming and increasing cell plasticity of primary multipotent mesenchymal stromal cells (MMSC)
  • as an inhibitor of DNA methyltransferase (DNMTi) in human retinal pigment epithelial ARPE-19 cells
  • as a DNA methyltransferase inhibitor in C33A2 cells to test its effect on papillomavirus late gene expression (HPV16)

Allgemeine Beschreibung

RG108, a non-nucleoside analog is also called [2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl) propanoic acid.

Biologische Aktivit?t

Non-nucleoside DNA methyltransferase inhibitor that blocks the enzyme active site. Inhibits DNA methylation in human cancer cell lines in vitro without detectable toxicity. Demethylates and reactivates epigenetically silenced tumor suppressor genes.

RG108 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


RG108 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 147)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32951 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29884 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 965 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32079 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22883 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15354 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739
info@dycnchem.com China 52849 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58

48208-26-0()Verwandte Suche:


  • (S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid
  • RG108/RG-108
  • (S)-3-(Indol-3-yl)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propanoic acid
  • N-Phthaloyl-L-tryptophan
  • 1H-Indole-3-propanoic acid, α-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, (αS)-
  • N-Phthaloyl-L-tryptophan (S)-3-(Indol-3-yl)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propanoic acid
  • DNA Methyltransferase Inhibitor
  • N-Phthalyl-L-tryptophan
  • RG108 >98%
  • RG108/DNA Methyltransferase Inhibitor/N-Phthalyl-L-tryptophan
  • 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid
  • CS-1518
  • RG-108;RG 108;N-PHTHALYL-L-TRYPTOPHAN
  • N-Phthalyl-L-tryptophan>
  • 108
  • RG108 USP/EP/BP
  • 1H-Indole-3-propanoicacid, a-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-,(aS)-
  • N-phthalimide-L-tryptophan
  • R 108
  • 48208-26-0
  • Inhibitors
  • DNA Methyltransferase Inhibitor
  • Epigenetics
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