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2-Chloro-5-hydroxypyrimidine

2-Chloro-5-hydroxypyrimidine Struktur
4983-28-2
CAS-Nr.
4983-28-2
Englisch Name:
2-Chloro-5-hydroxypyrimidine
Synonyma:
2-Chloropyrimidin-5-ol;Piribedil Impurity 17;2-Chloro-5-pyrimidinol;5-PyriMidinol,2-chloro-;2-Chloro-5-hydroxypyrimidine;2-Chloro-5-hydroxypyrimid...;2-Chloro-5-hydroxypyrimidine 98%;5-Pyrimidinol, 2-chloro- (7CI,8CI,9CI);2-Chloro-5-hydroxypyrimidine ISO 9001:2015 REACH;TIANFU-CHEM 2-Chloro-5-hydroxypyrimidine 4983-28-2
CBNumber:
CB0947875
Summenformel:
C4H3ClN2O
Molgewicht:
130.53
MOL-Datei:
4983-28-2.mol

2-Chloro-5-hydroxypyrimidine Eigenschaften

Schmelzpunkt:
195-196 °C
Siedepunkt:
328.1±15.0 °C(Predicted)
Dichte
1.513±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
6.17±0.23(Predicted)
CAS Datenbank
4983-28-2(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
HS Code  29335990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

2-Chloro-5-hydroxypyrimidine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

2-Chloro-5-hydroxypyrimidine is an intermediate used to synthesize tandospirone derivatives with anxiolytic activities.

Synthese

2-Chloro-5-methoxypyrimidine (0.46 g, 3.18 mmol) in methylene chloride (10 mL) was treated with 1.0 N boron tribromide (16 mL, 16 mmol) at room temperature. The solution was stirred overnight. After that, the reaction was partitioned between saturated NaHCO3 and DCM. The aqueous layer was extracted with additional DCM. Combined the organic layers and dried (MgSO4), filtered, and concentrated to obtain the crude product. The residue was purified by flash column chromatography on silica gel to give 2-Chloro-5-hydroxypyrimidine.2-Chloro-5-hydroxypyrimidine

2-Chloro-5-hydroxypyrimidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2-Chloro-5-hydroxypyrimidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 267)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Boc Chemical Co., Ltd.
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4983-28-2()Verwandte Suche:


  • 2-Chloro-5-hydroxypyrimidine
  • 5-Pyrimidinol, 2-chloro- (7CI,8CI,9CI)
  • 2-Chloro-5-hydroxypyrimid...
  • 5-PyriMidinol,2-chloro-
  • 2-Chloropyrimidin-5-ol, 2-Chloro-5-hydroxy-1,3-diazine
  • 2-Chloro-5-hydroxypyrimidine 98%
  • 2-Chloro-5-pyrimidinol
  • 2-Chloro-5-hydroxypyrimidine ISO 9001:2015 REACH
  • Piribedil Impurity 17
  • TIANFU-CHEM 2-Chloro-5-hydroxypyrimidine 4983-28-2
  • 2-Chloropyrimidin-5-ol
  • 4983-28-2
  • 1983-28-2
  • Heterocycle-Pyrimidine series
  • PYRIMIDINE
  • pharmacetical
  • Pyrimidines
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