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Defluoro O-Methyl Dolutegravir

Defluoro O-Methyl Dolutegravir Struktur
2244245-33-6
CAS-Nr.
2244245-33-6
Englisch Name:
Defluoro O-Methyl Dolutegravir
Synonyma:
Defluoro O-Methyl Dolutegravir;(4R,12aS)-N-(4-fluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6, 8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber:
CB09401361
Summenformel:
C21H22FN3O5
Molgewicht:
415.41
MOL-Datei:
2244245-33-6.mol

Defluoro O-Methyl Dolutegravir Eigenschaften

Siedepunkt:
690.8±55.0 °C(Predicted)
Dichte
1.41±0.1 g/cm3(Predicted)
pka
11.11±0.40(Predicted)

Sicherheit

Defluoro O-Methyl Dolutegravir Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Defluoro O-Methyl Dolutegravir is an intermediate in the synthesis of Defluoro Dolutegravir (D228715) which is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Defluoro O-Methyl Dolutegravir Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Defluoro O-Methyl Dolutegravir Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • Defluoro O-Methyl Dolutegravir
  • 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-, (4R,12aS)-
  • (4R,12aS)-N-(4-fluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6, 8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine9-carboxamide
  • 2244245-33-6
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