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2-[(Hydroxyimino)methyl]-1-methylpyridinium

2-[(hydroxyimino)methyl]-1-methylpyridinium  Struktur
6735-59-7
CAS-Nr.
6735-59-7
Bezeichnung:
2-[(Hydroxyimino)methyl]-1-methylpyridinium
Englisch Name:
2-[(hydroxyimino)methyl]-1-methylpyridinium
Synonyma:
Pralidoxime;1-Methylpyridinium-2-carbaldehydeoxime;2-[(hydroxyimino)methyl]-1-methylpyridinium;2-[(2E)-2-(hydroxyimino)ethyl]-1-methylpyridin-1-ium iodide
CBNumber:
CB0921226
Summenformel:
C7H9N2O+
Molgewicht:
137.15916
MOL-Datei:
6735-59-7.mol

2-[(Hydroxyimino)methyl]-1-methylpyridinium Eigenschaften

Sicherheit

Giftige Stoffe Daten 6735-59-7(Hazardous Substances Data)

2-[(Hydroxyimino)methyl]-1-methylpyridinium Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Before aging occurs, patients can be treated with pralidoxime, which breaks the phosphorus–enzyme complex and regenerates the enzyme. Pralidoxime is a strong nucleophile. It reactivates phosphorylated enzymes in a two-staged reaction. First, a complex is formed between the oximate ion and the phosphorylated enzyme. Second, enzyme activity is restored and phosphorylated oxime is formed. The high reactivating ability of pralidoxime is attributed to its ability to combine with a negatively charged group on the surface of an enzyme and a high level of molecular correlation between oxime and phosphorylated cholinesterase. It is possible that oximes may react directly with the inhibitor, turning it into a harmless compound as well as reactivating the inhibitory enzyme both in blood and in tissue.

Verwenden

Pralidoxime is used for treating organophosphate poisonings, paralysis of skeletal muscle, and in general for cholinesterase crisis.

Definition

ChEBI: A pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2.

2-[(Hydroxyimino)methyl]-1-methylpyridinium Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2-[(Hydroxyimino)methyl]-1-methylpyridinium Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 7)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
TargetMol Chemicals Inc.
+8613564774135
zijue.cai@tsbiochem.com United States 19885 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-87576359 15353716720
1039@dideu.com China 10009 58
Suzhou Haiben Pharmaceutical Co., Ltd 14760821013 13564957716
1816280386@qq.com China 7992 58
TargetMol Chemicals Inc. 15002134094
marketing@targetmol.cn China 19704 58

  • 2-[(hydroxyimino)methyl]-1-methylpyridinium
  • 1-Methylpyridinium-2-carbaldehydeoxime
  • Pralidoxime
  • 2-[(2E)-2-(hydroxyimino)ethyl]-1-methylpyridin-1-ium iodide
  • 6735-59-7
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