Benoxaprofen Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
A non-steroidal anti-inflammatory ophthalmic agent.
Definition
ChEBI: A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group. It was used as a non-steroidal anti-inflammatory drug until 1982 when it was withdrawn from the market due to adverse side-effects inc
uding liver necrosis, photosensitivity, and carcinogenicity in animals.
Weltgesundheitsorganisation (WHO)
Benoxaprofen, a nonsteroidal antiinflammatory agent, was
introduced in 1980 for the treatment of rheumatic disorders. Following reports of
serious adverse effects, some of which were fatal, it was withdrawn in several
countries prior to worldwide withdrawal by the manufacturer in 1982.
Sicherheitsprofil
Poison by ingestion, subcutaneous, and intraperitoneal routes. Moderately toxic to humans by ingestion.Human systemic effects by ingestion: jaundice and gynecomastia (excessive development of the male mammary glands), changes in kidney tubules, decreased
Benoxaprofen Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte