N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid
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- CAS-Nr.
- 65-61-2
- Bezeichnung:
- N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid
- Englisch Name:
- ACRIDINE ORANGE
- Synonyma:
- AO;AOX1;Lysotraker;CI NO 46005;BASIC ORANGE;-Cellstain-Ao;Euchrysine 3r;EUCHRYSINE 3RX;acridineoranger;RHODULINE ORANGE
- CBNumber:
- CB0747468
- Summenformel:
- C17H20ClN3
- Molgewicht:
- 301.82
- MOL-Datei:
- 65-61-2.mol
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N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid Eigenschaften
- Schmelzpunkt:
- 284-287 °C(lit.)
- Dichte
- 1.001 g/mL at 20 °C
- Brechungsindex
- n20/D 1.338
- storage temp.
- -20°C
- L?slichkeit
- Soluble in water, ethanol, dimethyl sulfoxide
- Aggregatzustand
- Powder
- pka
- -3.2, 10.5(at 25℃)
- Colour Index
- 46005
- Farbe
- orange to red
- maximale Wellenl?nge (λmax)
- 500 nm
- BRN
- 3734978
- Major Application
- Adhesives; aluminophosphate crystalline materials; detecting clay particles; display device; evaluating fiber surface characteristics; glass matrixes; imaging material; inks; lasers; recording materials; photoresists; textiles; thin films; tracers for hydrology; wiring boards
- Biologische Anwendungen
- Detecting cancer cells,spores,human papilloma virus (HPV),stress biomarkers; treating amyloid associated diseases,lupus,pathogen infections; apoptosis assays; cytotoxicity assays
- CAS Datenbank
- 65-61-2
- EPA chemische Informationen
- C.I. Basic Orange 14 (65-61-2)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
22-24/25 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
AR7601000 |
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| HS Code |
32041300 |
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| Toxizit?t |
dnd-mus:ast 20 mmol/L BBACAQ 374,96,74 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H341 |
Kann vermutlich genetische Defekte verursachen. |
Keimzellmutagenit?t |
Kategorie 2 |
Warnung |
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P201,P202, P281, P308+P313, P405,P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
dark orange to brown powder
Verwenden
Acridine orange is a dye that interacts with DNA and RNA by intercelation or electrostatic attraction. This cationic dye has been used as a fluorescent stain for nucleic acids in agarose and polyacrylamide gels.
synthetische
4,4 ‘-Bis (N, N-dimethyl) aminodiphenylmethane obtained dinitration of 4,4′ – bis (N, N-dimethyl) amino-2 ‘- dinitro-diphenyl methane reduction, and with an acid of heat, so that the diamino compound is cyclized product is oxidized and then cyclized and converted into zinc chloride double salt.
Sicherheitsprofil
Mutation data reported. Whenheated to decomposition it emits very toxic fumes of HCl,Cl??, and NOx.
Enzyminhibitor
This cell-permeable dye (FWfree-base = 265.36 g/mol; CAS 65-61-2), also known as N,N,N',N'-tetramethylacridine-3,6-diamine, is an intercalator that binds tightly to nucleic acids. Binding to DNA is characterized by excitation maximum at 502 nm (cyan) and an emission maximum at 525 nm, producing a green fluorescence. (A 120 μM solution of acridine orange will detect 25-50 ng DNA per band in an agarose or polyacrylamide gel.) Binding to RNA is characterized by an excitation maximum at 460 nm and the emission maximum is located at 650 nm, yielding a reddish-orange fluorescence. Acridine orange also penetrates acidic compartments (e.g., lysosomes and phagolysosomes); upon protonation, the dye emits orange light when excited by blue light.
N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 136)Lieferanten
65-61-2(N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid)Verwandte Suche:
- 3,6-BIS(DIMETHYLAMINO)ACRIDINE HYDROCHLORIDE
- ACRIDINE ORANGE (E GURR)
- ACRIDINE ORANGE HYDROCHLORIDE
- ACRIDINE ORANGE N
- BASIC ORANGE
- BIS(DIMETHYLAMINO) ACRIDINE HYDROCHLORIDE
- AO
- CI NO 46005
- EUCHRYSINE 3RX
- rhodulineorangeno
- N,N,N',N'-tetramethylacridin-3,6-yldiamine hydrochloride
- ACRIDINE ORANGE SOLUTION
- ACRIDINE ORANGE HYDROCHLORIDE SOLUTION, ~1% IN WATER
- ACRIDINE ORANGE FOR MICROSCOPY
- ACRIDINE ORANGE HYDROCHLORIDE HYDRATE, F OR MICROSCOPY
- ACRIDINE ORANGE HYDROCHLORIDE HYDRATE 80%
- -Cellstain-Ao
- -Cellstain-AoSolution
- ACRIDING ORANGE HYDROCHLORIDE
- 3,6-Bis(dimethylamino) acridine, zinc chloride double salt
- Acridine Orange, hydrochloride hydrate, ca. 80 % dye content, pure
- AOX1
- acridine orange hydrochloride solution
- 3,6-Bis(dimethylamino)acridine,hydrochloride,hydrate,aqueoussolution
- ACRIDINE ORANGE N-HYRATE
- Basic orange 14 (C.I. 46005)
- Acridine Orange solution hydrochloride
- Acridine Orange hydrate hydrochloride
- Acridine Orange, hydrochloride hydrate,pure,ca. 80 % dye content
- Acridine Orange hydrochloride solution,3,6-Bis(dimethylamino)acridine hydrochloride
- ACRIDINE ORANGE HYDROCHLORIDE HYDRATE PURUM, FOR MICROSCOPY ((FL., HIST.)) 98%
- RHODULINE ORANGE
- 3,6-BIS(DIMETHYLAMINO)ACRIDINE, HCL
- 3,6-acridinediamine, N,n,n0,n0-tetramethyl-,
monohydrochloride
- Acridine,
3,6-bis(dimethylamino)-, Hydrochloride
- Acridine,
3,6-bis(dimethylamino)-, Monohydrochloride
- Euchrysine 3r
- Sumitomo Acridine Orange No
- Sumitomo
acridine Orange Rk Conc
- 3,6-Acridinediamine,N,N,N’,N’-tetramethyl-,monohydrochloride
- 3,6-bis(dimethylamino)-acridinmonohydrochloride
- 6-acridinediamine,n,n,n’,n’-tetramethyl-monohydrochloride
- acridineorangeno
- acridineorangens
- acridineoranger
- c.i.basicorange14
- 6-acridinediamine
- 6-Bis(dimethylamino)acridine hydrochloride 3
- Lysotraker
- N’-Tetramethyl-3
- N,N,N',N'-Tetramethyl-3,6-acridinediamine hydrochloride
- N3,N3,N6,N6-Tetramethylacridine-3,6-diamine hydrochloride
- Acridine Orange hydrochloride?, >99%
- N3,N3,N6,N6-tetramethylacridine-3,6-diamine chloride
- Cellstain AO Solution (1mg/ml H2O)
- Acridine Orange Solution [for Cell Staining]
- C.I.Basic Orange 14:C.I.46005
- Acridine orange hydrochloride, hydrate, ≥98% (HPLC)
