Misoprostol Acid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R45:Kann Krebs erzeugen.
R60:Kann die Fortpflanzungsf?higkeit beeintr?chtigen.
R61:Kann das Kind im Mutterleib sch?digen.
R25:Giftig beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Beschreibung
Misoprostol is a prostaglandin E
1 analog with agonist activity mediated by EP
2, EP
3, and EP
4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED
50 = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC
50 = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC
50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-
486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-
1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.
Chemische Eigenschaften
Pale Yellow Gel
Verwenden
Misoprostol Acid is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.
Misoprostol Acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
