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Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- Struktur
1332881-26-1
CAS-Nr.
1332881-26-1
Englisch Name:
Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-
Synonyma:
ABI-231;Sabizabulin;sabizabulin(VERU-111);Sabizabulin/VERU-111/ABI-231;Sabizabulin (Synonyms: VERU-111;2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-Methanone;Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-;VERU-111 (1H-indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl)methanone
CBNumber:
CB05569748
Summenformel:
C21H19N3O4
Molgewicht:
377.39
MOL-Datei:
1332881-26-1.mol

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- Eigenschaften

Siedepunkt:
688.1±55.0 °C(Predicted)
Dichte
1.306±0.06 g/cm3(Predicted)
storage temp. 
4°C, away from moisture and light
L?slichkeit
Soluble in DMSO
pka
10.82±0.10(Predicted)
Aggregatzustand
Solid
Farbe
Light yellow to yellow

Sicherheit

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Sabizabulin (VERU-111) is a potent, orally bioavailable, and well-tolerated microtubule inhibitor that Veru Inc. is currently developing. It can inhibit the growth of ovarian tumors and completely suppress tumor metastasis in vivo, with efficacy comparable to that of paclitaxel, the current first-line treatment for ovarian cancer. VERU-111 can block the polymerization of tubulin and is not a substrate for multi-drug resistance mechanisms.

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 37)Lieferanten
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BOC Sciences 		+1-631-485-4226
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Nanjing Bicbiotechnology Co., Ltd 		+86-2552131256 +86-18251840740
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Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139
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Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822
 czbjpharma@126.com China 18478 58
  • Sabizabulin (Synonyms: VERU-111
  • ABI-231
  • Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-
  • Sabizabulin
  • sabizabulin(VERU-111)
  • VERU-111 (1H-indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl)methanone
  • 2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-Methanone
  • Sabizabulin/VERU-111/ABI-231
  • 1332881-26-1
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