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Doripenem hydrate

Doripenem hydrate Struktur
364622-82-2
CAS-Nr.
364622-82-2
Englisch Name:
Doripenem hydrate
Synonyma:
Finibax;2H5]-Doripenem;DoripeneM Crude;doripenem hydrate;S 4661 monohydrate;Doripenem Hydrate (S 4661);Doripenem hydrate USP/EP/BP;Doripenem monohydrate, >=99%;DORIPENEM MONOHYDRATE STERILE;Doripenem Hydrate/Doribax/S-4661/Finibax
CBNumber:
CB0511313
Summenformel:
C15H26N4O7S2
Molgewicht:
438.51
MOL-Datei:
364622-82-2.mol

Doripenem hydrate Eigenschaften

Schmelzpunkt:
173°C(dec.)(lit.)
storage temp. 
2-8°C
L?slichkeit
H2O: soluble5mg/mL, clear (warmed)
Aggregatzustand
powder
Farbe
white to beige
PH
Dissolve 0.3g of Doripenem Hydrate in 30mL of water: the pH of the solution is between 4.5 and 6.0.
BRN 
15340136
InChIKey
NTUBEBXBDGKBTJ-WGLOMNHJSA-N
CAS Datenbank
364622-82-2(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
HS Code  2935.90.9500
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H341 Kann vermutlich genetische Defekte verursachen. Keimzellmutagenit?t Kategorie 2 Warnung P201,P202, P281, P308+P313, P405,P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P281 Vorgeschriebene pers?nliche Schutzausrüstung verwenden.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Doripenem hydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Doripenem hydrate is a carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.
Doripenem hydrate was first approved by Pharmaceuticals and Medical Devices Agency of Japan (PMDA) on July 25, 2005, then approved by the U.S. Food and Drug Administration (FDA) on Oct 12, 2007, and approved by European Medicines Agency (EMA) on July 25, 2008. It was developed by Shionogi and Janssen, then marketed as Finibax® in Japan and as Doribax® in the US by Shionogi and as Doribax® by Janssen in BE.

Chemische Eigenschaften

Doripenem Hydrate occurs as a white to pale yellow-brown-white crystalline powder. It is sparingly soluble in water, slightly soluble in methanol, and practically insoluble in ethanol (99.5). It is gradually colored to pale yellow-brown-white by light.

Verwenden

Doripenem (doripenem monohydrate) is an ultra-broad spectrum injectable antibiotic. It is a beta-lactam and belongs to the subgroup of carbapenems. It is particularly active against Pseudomonas aeruginosa

Biochem/physiol Actions

Doripenem is an ultra-broad spectrum carbopenem antibiotic. Doripenem is active against both gram-positive and gram-negative bacteria.

Doripenem hydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Doripenem hydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 223)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@
sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32956 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 965 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845
sales@amoychem.com China 6383 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Beijing Yibai Biotechnology Co., Ltd
0086-182-6772-3597
sales04@yibaibiotech.com CHINA 419 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58

364622-82-2()Verwandte Suche:


  • (+)-(4r,5s,6s)-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-3-[[(3s,5s)-5-[(sulfamoylamino)-methyl]-3-pyrrolidinyl]thio]-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
  • doripenem hydrate
  • DoripeneM Crude
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, hydrate
  • (4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • Doripenem monohydrate, >=99%
  • (4R,5S,6S)-6-((R)-1-Hydroxyethyl)-4-methyl-7-oxo-3-(((3S,5S)-5-((sulfamoylamino)methyl)pyrroli
  • S 4661 monohydrate
  • (4R,5S,6S)-6-((R)-1-Hydroxyethyl)-4-methyl-7-oxo-3-(((3S,5S)-5-((sulfamoylamino)methyl)pyrrolidin-3-yl)thio)-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
  • Doripenem hydrate USP/EP/BP
  • DORIPENEM MONOHYDRATE STERILE
  • Doripenem Hydrate (S 4661)
  • Doripenem monohydrateQ: What is Doripenem monohydrate Q: What is the CAS Number of Doripenem monohydrate Q: What is the storage condition of Doripenem monohydrate
  • 2H5]-Doripenem
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, hydrate (1:1), (4R,5S,6S)-
  • (4R,5S,6S)-3-[[(3S,5S)-5-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate (1:1)
  • Doripenem Hydrate/Doribax/S-4661/Finibax
  • Finibax
  • 364622-82-2
  • 34622-82-2
  • C15H24N4O6S2H2O
  • C15H26N4O7S2
  • Doribax, Doripenem monohydrate, S-4661, Finibax
  • Inhibitors
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