CS-968;BAPTA-AM;DAPTA-AM;BAPTA AM, >=98%;BAPTA/AM(BAPTA-AM);BAPTA-AM, Ca2+ chelator;BAPTA-AM, 10 mM in DMSO;BAPTA, AM *CAS 126150-97-8*;BAPTA/AM;BAPTAAM;BAPTA AM;BAPTA-AM;BAPTA, AM *UltraPure Grade* *CAS 126150-97-8*
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren. S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Off-White to Light Yellow Solid
Verwenden
BAPTA-AM is a lipophilic diester of BAPTA used for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE.
Fluorescence: max. Abs. 287nm; e x 10-3: 5.9
Allgemeine Beschreibung
BAPTA-AM inhibits free radical-mediated toxicity, enhances apoptosis in non-neuronal cells and protects neurons from ischemic damage. It regulates ion channels and blocks neuronal Ca2+-activated K+?channel currents. BAPTA-AM maintains intracellular Ca2+ homeostasis.
Biologische Aktivit?t
Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat No. 2786 ). Blocks hK v 1.5, hERG and hK v 1.3 channels (K i values are 1.23, 1.30 and 1.45 μ M respectively). Displays antithrombotic activity in vitro .
BAPTA-AM Upstream-Materialien And Downstream Produkte