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TOPO I HUMAN

TOPO I HUMAN Struktur
CAS-Nr.
Englisch Name:
TOPO I HUMAN
Synonyma:
TOPO(R) I;TOPO I HUMAN;TOPOISOMERASE I HUMAN;Topoisomerase I from vaccinia virus
CBNumber:
CB0451477
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

TOPO I HUMAN Eigenschaften

storage temp. 
-70°C
Aggregatzustand
liquid

Sicherheit

Kennzeichnung gef?hrlicher T
R-S?tze: 61
S-S?tze: 23-24/25-45-53
WGK Germany  1

TOPO I HUMAN Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Topoisomerase I human has been used for Topoisomerase I assay for screening inhibitors.

Allgemeine Beschreibung

Topoisomerase I (TOP1) is mapped to human chromosome 20q12. TOP1 is a 91 kDa type IB enzyme and consists of N-terminal highly charged domain, a core, linker domain and a C-terminal catalytic domain with Tyr-723 active site residue.

Biochem/physiol Actions

Topoisomerase I human (TOP1) interacts with DNA by wrapping and takes a bi-lobed conformation. TOPI is essential for normal development and transcriptional regulation. Variants in the TOP1 gene is observed in patients with colorectal cancer.

TOPO I HUMAN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


TOPO I HUMAN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 3)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969
sales@tomums.cn China 4696 58

  • TOPO I HUMAN
  • TOPOISOMERASE I HUMAN
  • TOPO(R) I
  • Topoisomerase I from vaccinia virus
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