3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE
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- CAS-Nr.
- 1005-24-9
- Englisch Name:
- 3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE
- Synonyma:
- 1-METHYLNICOTINAMIDE CHLORIDE;TRIA-662;Trionellamide chloride;TRIGONELLAMIDE CHLORIDE;TRIA-662, 10 mM in DMSO;nicotinamidemethochloride;nipecotamidemethochloride;1-Methylnicotine Chloride;Nicotinamide Impurity 127;nicotinamidemethylchloride
- CBNumber:
- CB0431956
- Summenformel:
- C7H9ClN2O
- Molgewicht:
- 172.61
- MOL-Datei:
- 1005-24-9.mol
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3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE Eigenschaften
- Schmelzpunkt:
- 207-209℃ (water acetone )
- storage temp.
- room temp
- L?slichkeit
- H2O: soluble15mg/mL, clear
- Aggregatzustand
- crystalline
- Farbe
- white
- Wasserl?slichkeit
- almost transparency
- Merck
- 14,9693
- CAS Datenbank
- 1005-24-9(CAS DataBase Reference)
3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Nicotinamide is a precursor of NAD and NADP , which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; ). It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability. Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.
Verwenden
Nicotinamide is a precursor of NAD and NADP , which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; ). It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability. Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.
Allgemeine Beschreibung
1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced mainly by nicotinamide N-methyltransferase (NNMT) and exhibits antithrombotic and anti-inflammatory effects.
l?uterung methode
Recrystallise it from MeOH. [Beilstein 22 III/IV 468, 22/2 V 80.]
3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 106)Lieferanten
1005-24-9()Verwandte Suche:
- NICOTINAMIDE CHLOROMETHYLATE
- N-METHYLNICOTINIC ACID AMIDE CHLORIDE SALT
- N1-METHYLNICOTINAMIDE CHLORIDE
- TRIGONELLAMIDE CHLORIDE
- 3-(aminocarbonyl)-1-methyl-pyridiniuchloride
- 3-carbamoyl-1-methyl-pyridiniuchloride
- nicotinamidemethochloride
- nicotinamidemethylchloride
- 1-METHYLPYRIDINE-3-CARBOXYLIC ACID AMIDE CHLORIDE
- 1-METHYLNICOTINAMIDE CHLORIDE SALT
- 3-CARBAMOYL-1-METHYLPYRIDINIUM CHLORIDE
- 3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE
- nipecotamidemethochloride
- n-methylnicotinamidechloride
- n-methylnicotinic acid amide chloride
- 3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE 98+%
- 3-Carbamoyl-1-methylpyridinium Chloride
1-Methylnicotinamide Chloride
Nicotinamide Chloromethylate
- 3-Carbamyl-1-methylpyridiniumChloride>
- 1-methylpyridin-1-ium-3-carboxamide hydrochloride
- Nicotinamide 1-Methyl Chloride
- Trionellamide chloride
- 3-Carbamoyl-1-methylpyridin-1-ium chloride
- 1-METHYLNICOTINAMIDE CHLORIDE
- 2-ACETYL-5-CHLORO-40-METHYLTHIANAPHTHENE
- TRIA-662
- inhibit,1-Methylnicotinamide,N-methylnicotinamide,Inhibitor,Endogenous Metabolite,TRIA 662,anti-inflammatory activity,antithrombotic activity,HMECs,TRIA-662,TRIA662
- 1-Methylnicotine Chloride
- Nicotinamide Impurity 127
- TRIA-662, 10 mM in DMSO
- 1005-24-9
- Urinary excretion product of niacin metabolism
- Pyridinium Compounds
- Analytical Chromatography Product Catalog
- Alphabetic
- Analytical Standards
- META - METH
- Pyridinium Compounds
