KDOAM-25 Chemische Eigenschaften,Einsatz,Produktion Methoden

Biochem/physiol Actions

KDOAM25 is a selective inihbitor of the KDM5 family histone demethylases JARID1A, JARID1B, JARID1C and JARID1D with IC50 values < 60 nM. JARID1A and JARID1B are independently overexpressed in some cancers with JARID1B (KDM5B, PLU1) also identified as a potential oncogene, a repressor of tumour repressor genes. JARID1C (KDM5C) and JARID1D (KDM5D) are located on the X- and Y-chromosomes respectively. KDOAM25′s closest off-target is JMJD2C (selectivity >400 fold). It shows no activity on other tested 2-OG family members, including FIH, NO66, MINA53 and PHD2. KDOAM25 is active in cells.

KDOAM-25 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

KDOAM-25 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32002	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38460	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19863	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9410	58
Shanghai hongqu biomedical technology co. LTD	88888888888	hongquchem@qq.com	China	5132	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	3982	58
cjbscvictory	13348960310 13348960310	3003867561@qq.com	China	9999	58

---

• KDOAM-25
• 4-Pyridinecarboxamide, 2-[[[2-[[2-(dimethylamino)ethyl]ethylamino]-2-oxoethyl]amino]methyl]-
• KDOAM-25 trihydrochloride
• KDOAM 25,KDOAM25
• 2230731-99-2