Proteasome Inhibitor XVI Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A cell-permeable, peptide vinyl sulfone that acts as a potent, irreversible inhibitor of proteasome activity. Covalently modifies the catalytically active β-subunits of the proteasome. Shown to inhibit the chymotrypsin-like (10-50 nM), trypsin-like (1-5 μM), and the peptidyl glutamyl peptide hydrolyzing (PGPH) (0.5-1 μM) activities of purified 20S proteasomes from rabbit muscle. Inhibits proteasomal degradation of deglycosylated MHC HLA-A2 heavy chain in US11+ cells (~50 μM).

Biochem/physiol Actions

Cell permeable: yes

Proteasome Inhibitor XVI Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Proteasome Inhibitor XVI Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Alabiotech Inc.	001-619-354-5251	sales@alabiotech-e.com	United States	972	60
Alpha Biopharmaceuticals Co., Ltd	0411-39042497	sales@alphabiopharm.com	China	1951	58

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