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Cholesta-5,24-dien-3-β-ol

DESMOSTEROL Struktur
313-04-2
CAS-Nr.
313-04-2
Bezeichnung:
Cholesta-5,24-dien-3-β-ol
Englisch Name:
DESMOSTEROL
Synonyma:
Desmostero;esmosterol;DESMOSTEROL;24-DEHYDROCHOLESTEROL;Cholesterol impurity B;desmosterol crystalline;Cholesta-5,24-dien-3-ol;5,24-Cholestadien-3β-ol;Cholesterol Impurity 12;5, 24-CHOLESTADIEN-3β-OL
CBNumber:
CB0307682
Summenformel:
C27H44O
Molgewicht:
384.65
MOL-Datei:
313-04-2.mol

Cholesta-5,24-dien-3-β-ol Eigenschaften

Schmelzpunkt:
121.5°, also reported as 119-119.5°
alpha 
D27 -41.0° (c = 1 in chloroform)
Siedepunkt:
483.2±14.0 °C(Predicted)
Dichte
1.00±0.1 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
15.03±0.70(Predicted)
Farbe
Wihte to Off-White

Sicherheit

WGK Germany  3

Cholesta-5,24-dien-3-β-ol Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Off-White Solid

Verwenden

24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called, desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions.[Cayman Chemical]

Definition

ChEBI: A cholestanoid that is cholesta-5,24-diene substituted by a beta-hydroxy group at position 3. It is an intermediate metabolite obtained during the synthesis of cholesterol.

Allgemeine Beschreibung

Desmosterol lacks a double bond between C24 and C25 compared to cholesterol. It is present in the membrane of spermatozoa and astrocytes and is the major brain sterol.

Cholesta-5,24-dien-3-β-ol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cholesta-5,24-dien-3-β-ol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 89)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923
1026@dideu.com China 8670 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58
Henan Aochuang Chemical Co.,Ltd.
+86-0371-63689365 +8618638391208
sales@aochuangchem.com China 9245 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522
overseasales@yongstandards.com China 11922 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33338 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58
Moxin Chemicals
+8617320513646
mike@molcoo.com China 9457 58

313-04-2(Cholesta-5,24-dien-3-β-ol)Verwandte Suche:


  • 3BETA-HYDROXY-5,24-CHOLESTADIENE
  • 5,24-CHOLESTADIEN-3BETA-OL
  • 24-DEHYDROCHOLESTEROL
  • DESMOSTEROL
  • Desmostero
  • Cholesta-5,24-dien-3beta-ol
  • Cholesta-5,24-dien-3-ol
  • Cholesta-5,24-dien-3-ol, (3beta)-
  • desmosterol crystalline
  • (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • 24-Dehydrocholesterol, 3β-Hydroxy-5,24-cholestadiene, 5,24-Cholestadien-3β-ol
  • 24,25-Didehydrocholesterol
  • (3S,8S,9S,10R,13R,14S,17R)-10,13-diMethyl-17-((R)-6-Methylhept-5-en-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • 3-hydroxy-5,24-cholestadiene
  • 5,24-Cholestadien-3β-ol
  • 3-HYDROXY-5,24-CHOLESTADIENE;DESMOSTEROL
  • Cholesterol Impurity 12
  • Cholesterol impurity B
  • Cholesterol EP Impurity B (Desmosterol)
  • Cholesta-5,24-dien-3-ol, (3β)-
  • (3β)-Cholesta-5,24-dien-3-ol
  • Cholesta-5,24-dien-3-ol,(3b)-
  • c h ole sta -5,24-d i e n-3β-ol (d e smoste rol)
  • esmosterol
  • 5, 24-CHOLESTADIEN-3β-OL
  • 3β-hydroxy-5,24-cholestadiene
  • Desmosterol 24-Dehydrocholesterol
  • 313-04-2
  • BioChemical
  • Metabolomics
  • Lipid Library
  • Metabolic Libraries
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Steroids
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