Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
TAPI 2 is a matrix metalloprotease (MMP) inhibitor, which inhibits merpin α and β homo-oligomers.
Biochem/physiol Actions
TAPI-2 is a potent inhibitor matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). It blocks the shedding of several cell surface proteins such as β-amyloid precursor protein, inhibits TNF-α release as well as a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands. TAPI-2 is considered a fairly broad metalloproteinase inhibitor, but it much more selective for TACE than GM6001.
Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte