2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
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- CAS-Nr.
- 123021-85-2
- Englisch Name:
- 2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
- Synonyma:
- GPR35 agonist 3;GPR35 Agonist, Compound 10;GPR35 Agonist, Compound 10 >=98% (HPLC);2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid;2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid;Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinylidene)methyl]phenoxy]-;2-{4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]p
henoxy}acetic acid
- CBNumber:
- CB02750482
- Summenformel:
- C12H9NO5S
- Molgewicht:
- 279.27
- MOL-Datei:
- 123021-85-2.mol
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2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Eigenschaften
- Dichte
- 1.550±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: ≥5mg/mL at ~60°C
- Aggregatzustand
- powder
- pka
- 3.08±0.10(Predicted)
- Farbe
- white to tan
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
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| R-S?tze: |
36 |
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| S-S?tze: |
26 |
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| WGK Germany |
3 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
GPR35 Agonist, Compound 10, may be used in GPR35-mediated cell signaling studies.
Biochem/physiol Actions
GPR35 agonist Compound 10 is a GPR35 agonist the binds with higher affinity than other known agonists, such as kynurenic acid and zaprinast. Compound 10 was more potent than zaniprast (pEC50 = 5.3 vs 4.18) for recombinantly expressed human GPR35, and unlike zaprinast, is equipotent for human and rat GPR35
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 16)Lieferanten
- 2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
- GPR35 Agonist, Compound 10
- 2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid
- GPR35 Agonist, Compound 10 >=98% (HPLC)
- 2-{4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]p
henoxy}acetic acid
- GPR35 agonist 3
- Acetic acid, 2-[4-[(2,4-dioxo-5-thiazolidinylidene)methyl]phenoxy]-
- 123021-85-2
