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Sofosbuvir IMpurity B

Sofosbuvir IMpurity B Struktur
1496552-51-2
CAS-Nr.
1496552-51-2
Englisch Name:
Sofosbuvir IMpurity B
Synonyma:
Sofosbuvir impurity K;Sofosbuvir IMpurity B;Sofosbuvir Chloro Analog;Sofosbuvir Chloro Analogue;sofosbuvir impurity Y008005-K;Sofosbuvir Ph.Int Impurity B(Chloro Sofosbuvir);L-Alanine, N-[[P(S),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-chloro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;(2S)-isopropyl 2-(((((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;(S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
CBNumber:
CB02716563
Summenformel:
C22H29ClN3O9P
Molgewicht:
545.91
MOL-Datei:
1496552-51-2.mol

Sofosbuvir IMpurity B Eigenschaften

Dichte
1.43±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
Solid
pka
9.39±0.10(Predicted)
Farbe
Light yellow to yellow

Sicherheit

Sofosbuvir IMpurity B Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Chloro Sofosbuvir is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Sofosbuvir IMpurity B Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Sofosbuvir IMpurity B Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 52)Lieferanten
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  • Sofosbuvir IMpurity B
  • (S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
  • Sofosbuvir impurity K
  • Sofosbuvir Chloro Analogue
  • L-Alanine, N-[[P(S),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester
  • Sofosbuvir Chloro Analog
  • sofosbuvir impurity Y008005-K
  • (2S)-isopropyl 2-(((((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
  • ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-chloro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
  • Sofosbuvir Ph.Int Impurity B(Chloro Sofosbuvir)
  • 1496552-51-2
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