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ANTI-PKC BETA2

ANTI-PKC BETA2 Struktur
CAS-Nr.
Englisch Name:
ANTI-PKC BETA2
Synonyma:
Anti-PRKCZ;Anti-PKC β2;ANTI-PKC BETA2;ANTI-PROTEIN KINASE C BETA2;Anti-PRKCZ antibody produced in rabbit;Monoclonal Anti-PRKCZ antibody produced in mouse;Anti-Protein KinaseCβ2 antibody produced in rabbit;Monoclonal Anti-Protein KinaseCβ2 antibody produced in mouse
CBNumber:
CB0271581
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-PKC BETA2 Eigenschaften

storage temp. 
−20°C
Aggregatzustand
buffered aqueous solution
Biologische Quelle
rabbit

Sicherheit

WGK Germany  3

ANTI-PKC BETA2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-Protein Kinase C β2 antibody may be used for immunoblotting at a working dilution of 1:8000 using rat brain cytosolic extract. It is suitable for protein microarray.

Allgemeine Beschreibung

Protein Kinase C (PKC, 76-93 kD) is a family of Ser/Thr specific protein kinases that perform key functions in numerous signalling pathways, in biological systems, through their various isoforms. The conventional PKC isoforms (cPKC) are PKC-α, β1, β2 and γ; activated by phosphatidylserine, calcium or phorbol esters. Proteolysis of PKC in vivo is thought to be mediated by calpains I and II. Calpains cleave PKC in the V3 hinge region to produce two distinct fragments, one comprising the N-terminal regulatory domain (30 kD) and the other fragment containing the C-terminal kinase domain (50 kD) that is catalytically active. Multiple functions such as, cellular and vascular regulations, angiogenesis, cell growth, apoptosis, changes in basement membrane thickness, extracellular matrix organisation, MAPK signalling, are attributed to PKC isoforms. These varied functions implicate PKC isoforms in cardiac hypertrophies and diabetic nephropathy and cardiovascular complications.
Anti-Protein Kinase C β2 antibody specifically recognizes an epitope located within the amino acid residues 660-673 at the C-terminal variable (V5) region of PKCβ2 (80 kDa).

ANTI-PKC BETA2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-PKC BETA2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 3)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Neobioscience Co., Ltd. --
info@neobioscience.com CHINA 6682 58
Riedel-de Haen AG --
United States 6773 87
SIGMA-RBI --
Switzerland 6896 91

  • ANTI-PROTEIN KINASE C BETA2
  • ANTI-PKC BETA2
  • Monoclonal Anti-Protein KinaseCβ2 antibody produced in mouse
  • Anti-PKC β2
  • Anti-Protein KinaseCβ2 antibody produced in rabbit
  • Monoclonal Anti-PRKCZ antibody produced in mouse
  • Anti-PRKCZ
  • Anti-PRKCZ antibody produced in rabbit
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