N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
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- CAS-Nr.
- 289472-81-7
- Englisch Name:
- N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
- Synonyma:
- Bortezomib EP IMP M;Bortezomib USP IMP J;Bortezomib Impurity D;Bortezomib Impurity J;Bortezomib Impurity 48;Bortezomib impurity 90;Bortezomib USP Impurity J;BortezomibHydroxy(1S,2S)-Isomer;Bortezomib USP Related Compoud J;(S)-Hydroxy Des(boric Acid) BortezoMib
- CBNumber:
- CB02661665
- Summenformel:
- C19H24N4O3
- Molgewicht:
- 356.42
- MOL-Datei:
- 289472-81-7.mol
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N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Eigenschaften
- Siedepunkt:
- 672.0±55.0 °C(Predicted)
- Dichte
- 1.199±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 11.90±0.46(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
Sicherheit
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
(S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 71)Lieferanten
289472-81-7()Verwandte Suche:
- 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
- (S)-Hydroxy Des(boric Acid) BortezoMib
- (N-[(1S)-1-hydroxy-3-Methylbutyl]-Nα-(pyrazin-2-ylcarbonyl)-L-phenylalaninaMide
- Bortezomib Impurity 48
- Bortezomib Impurity J
- N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
- Bortezomib USP IMP J
- Bortezomib Impurity D
- Bortezomib USP Related Compoud J
- N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide
- N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-pyrazi
- Bortezomib USP Impurity J
- Bortezomib Related Compund J/ (S,S)-Bortezomib Hydroxyisopentyl Amide Analog (Bortezomib Hydroxy S,S-Isomer Impurity)
- BortezomibHydroxy(1S,2S)-Isomer
- (S,S)-Bortezomib Hydroxyisopentyl Amide Analog
- Bortezomib EP IMP M
- N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylprop
- N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenyl
- N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
- Bortezomib impurity 90
- 289472-81-7
- Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
