CAY10622 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Two Rho-associated kinases (ROCK), ROCK1 and ROCK2, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. CAY10622 is a potent, ureidobenzamide inhibitor of ROCK1 and ROCK2 with IC₅₀ values of 6 and 4 nM, respectively. It is inactive (showing greater then 100-fold selectivity) against an additional 44 kinases.

Verwenden

Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. CAY10622 is a potent, ureidobenzamide inhibitor of ROCK-I and ROCK-II kinases with IC50 values of 6 and 4 nM, respectively. It is inactive (showing greater then 100-fold selectivity) against an additional 44 kinases.[Cayman Chemical]

CAY10622 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CAY10622 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	12952	65
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9803	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19784	58
Cayman Chemical Company	800-364-9897	sales@caymanchem.com	China	27736	58
Santa Cruz Biotechnology Inc	60936350	scbt@scbt.com	China	222068	58

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• CAY10622
• BenzaMide, 3-[[[[[4-(aMinocarbonyl)phenyl]aMino]carbonyl]aMino]Methyl]-N-(1,2,3,4-tetrahydro-7-isoquinolinyl)-
• 3-[[(4-carbamoylphenyl)carbamoylamino]methyl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide
• CAY10622 Exclusive
• ROCK-IN-10
• 1038549-25-5